Evaluation of Antimalarial Potential of Extracts from Alstonia boonei and Carica papaya in Plasmodium berghei‐Infected Mice

FO Atanu, FM Idih, CO Nwonuma… - Evidence‐Based …, 2021 - Wiley Online Library
Extracts of Alstonia boonei and Carica papaya are used in herbal medicine for the treatment
of malaria. This work investigated the phytochemical, antioxidant, and antimalarial effects of …

An Allosteric Inhibitory Potential of Triterpenes from Combretum racemosum on the Structural and Functional Dynamics of Plasmodium falciparum Lactate …

WM Oluyemi, BB Samuel, AT Adewumi… - Chemistry & …, 2022 - Wiley Online Library
Multidrug resistance is a significant drawback in malaria treatment, and mutations in the
active sites of the many critical antimalarial drug targets have remained challenging …

[HTML][HTML] Reversing memory/cognitive impairment with medicinal plants targeting inflammation and its crosstalk with other pathologies

SEB Tyler, LDK Tyler - Brain Disorders, 2023 - Elsevier
Inflammation has a key role in driving memory/cognitive impairment in conditions ranging
from Alzheimer's disease, vascular dementia, Parkinson's disease, traumatic brain injury …

Antimalarial potential, LC–MS secondary metabolite profiling and computational studies of Zingiber officinale

KO Faloye, MK Tripathi, SA Adesida… - Journal of …, 2024 - Taylor & Francis
Malaria is among the top-ranked parasitic diseases that pose a threat to the existence of the
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …

Derivation, Functionalization of (S)-Goniothalamin from Goniothalamus wightii and Their Derivative Targets SARS-CoV-2 MPro, SPro, and RdRp: A …

V Palani, S Chinnaraj, M Shanmugasundaram… - Molecules, 2022 - mdpi.com
The tracing of an alternative drug, Phytochemicals is a promising approach to the viral
threats that have emerged over the past two years. Across the world, herbal medicine is a …

Insights on inhibition of Plasmodium falciparum plasmepsin I by novel epoxyazadiradione derivatives–molecular docking and comparative molecular field analysis

M Thillainayagam, K Malathi, A Anbarasu… - Journal of …, 2019 - Taylor & Francis
In the present study, we have explored the anti-malarial potential of epoxyazadiradione, the
natural entity extracted from the neem seed oil and its chemical derivatives, against …

β-Amyrin and Benzene-1, 2, 4-trimethyl from Euphorbia hirta L. and Nauclea latifolia (Smith) Leaves Induce Dauer Diapause via Antagonist Inhibition of daf-12 …

OT Ogunmefun, OA Ogunojemite… - And Nauclea Latifolia …, 2023 - papers.ssrn.com
Introduction: Drug development in many countriesbegins with medicinal plants usage as
valuable materials. Euphorbia hirta (EH) and Nauclea latifolia (NL) are important medicinal …

[HTML][HTML] Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models

S Owumi, JO Olanlokun, B Wu, AM Duro-Ladipo… - Molecules, 2024 - mdpi.com
Agunmu (ground herbal medicine) is a form of West African traditional medicine consisting
of a cocktail of herbs. The goal of this study is to evaluate a formulation of Agunmu made …

Mechanism of antimalarial action and mitigation of infection-mediated mitochondrial dysfunction by phyto-constituents of Andrographis paniculata ((Burm f.) Wall. ex …

JO Olanlokun, AB Owolabi, A Odedeyi… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Andrographis paniculata (AP)((Burm f.) Wall. ex Nees) is a
medicinal plant, documented for its folkloric use in the treatment of malaria. Aim This study …

Alstoboonine, an Ulean-Type Indole Alkaloid from Alstonia boonei Leaves

M Grimm, R Börner, JN Addotey… - Journal of Natural …, 2023 - ACS Publications
Alstonia boonei De Wild is a common plant in West Africa used in traditional medicine for
various indications. While the stem bark has frequently been investigated, not much is …