Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression
N Ahangar Davoodi, S Najafi… - Frontiers in cell and …, 2022 - frontiersin.org
Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the
potential to affect vision, and can even be fatal in some children. While the tumor can be …
potential to affect vision, and can even be fatal in some children. While the tumor can be …
[HTML][HTML] High expression of RRM2 as an independent predictive factor of poor prognosis in patients with lung adenocarcinoma
CY Jin, L Du, AH Nuerlan, XL Wang, YW Yang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Ribonucleotide reductase subunit M2 may play a role as a potential prognostic biomarker in
several cancers. In this study, we evaluated whether RRM2 gene expression is associated …
several cancers. In this study, we evaluated whether RRM2 gene expression is associated …
Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer
DWH Ho, YM Tsui, KMF Sze, LK Chan, TT Cheung… - Cancer letters, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is heterogeneous, rendering its current curative treatments
ineffective. The emergence of single-cell genomics represents a powerful strategy in …
ineffective. The emergence of single-cell genomics represents a powerful strategy in …
Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis
V Fortino, L Wisgrill, P Werner… - Proceedings of the …, 2020 - National Acad Sciences
Contact dermatitis tremendously impacts the quality of life of suffering patients. Currently,
diagnostic regimes rely on allergy testing, exposure specification, and follow-up visits; …
diagnostic regimes rely on allergy testing, exposure specification, and follow-up visits; …
Eleven genes associated with progression and prognosis of endometrial cancer (EC) identified by comprehensive bioinformatics analysis
JH Liu, SL Zhou, SY Li, Y Jiang, YC Wan, XL Ma… - Cancer Cell …, 2019 - Springer
Background Endometrial cancer (EC) is one of the female malignant tumors. Endometrial
cancer predominately affects post-menopausal women. Bioinformatics analysis has been …
cancer predominately affects post-menopausal women. Bioinformatics analysis has been …
[HTML][HTML] Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma
WC Cheng, CY Chang, CC Lo, CY Hsieh, TT Kuo… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Lung adenocarcinoma (LUAD) is an aggressive disease with high propensity of
metastasis. Among patients with early-stage disease, more than 30% of them may relapse or …
metastasis. Among patients with early-stage disease, more than 30% of them may relapse or …
Single-cell transcriptomics identifies a unique entity and signature markers of transit-amplifying cells in human corneal limbus
JM Li, S Kim, Y Zhang, F Bian, J Hu… - … & visual science, 2021 - iovs.arvojournals.org
Purpose: Differentiated from adult stem cells (ASCs), transit-amplifying cells (TACs) play an
important role in tissue homeostasis, development, and regeneration. This study aimed to …
important role in tissue homeostasis, development, and regeneration. This study aimed to …
LncRNA HOTAIR facilitates proliferation and represses apoptosis of retinoblastoma cells through the miR-20b-5p/RRM2/PI3K/AKT axis
K Fu, K Zhang, X Zhang - Orphanet Journal of Rare Diseases, 2022 - Springer
Purpose Retinoblastoma (RB) represents an adolescent eye malignancy. Long non-coding
RNA (LncRNA) HOTAIR shows aberrant expression in many malignancies. This research …
RNA (LncRNA) HOTAIR shows aberrant expression in many malignancies. This research …
Bioinformatics analysis revealing prognostic significance of RRM2 gene in breast cancer
W Chen, L Yang, L Xu, L Cheng, Q Qian… - Bioscience …, 2019 - portlandpress.com
Background: Ribonucleotide reductase M2 subunit (RRM2) plays vital roles in many cellular
processes such as cell proliferation, invasiveness, migration, angiogenesis, senescence …
processes such as cell proliferation, invasiveness, migration, angiogenesis, senescence …
RRM2 elicits the metastatic potential of breast cancer cells by regulating cell invasion, migration and VEGF expression via the PI3K/AKT signaling
S Zhuang, L Li, Y Zang, G Li… - Oncology letters, 2020 - spandidos-publications.com
Breast cancer is the second leading primary cause for cancer‑related mortality among
women and metastasis to the brain is a disastrous event for patients with increasing …
women and metastasis to the brain is a disastrous event for patients with increasing …