Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …
important roles in growth and development, tissue and organ regeneration, as well as …
Animal models of diabetic retinopathy
AM Olivares, K Althoff, GF Chen, S Wu… - Current diabetes …, 2017 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR) is one of the most common
complications associated with chronic hyperglycemia seen in patients with diabetes mellitus …
complications associated with chronic hyperglycemia seen in patients with diabetes mellitus …
Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression
DB Gurevich, CE Severn, C Twomey… - The EMBO …, 2018 - embopress.org
Wound angiogenesis is an integral part of tissue repair and is impaired in many pathologies
of healing. Here, we investigate the cellular interactions between innate immune cells and …
of healing. Here, we investigate the cellular interactions between innate immune cells and …
The zebrafish eye—a paradigm for investigating human ocular genetics
R Richardson, D Tracey-White, A Webster, M Moosajee - Eye, 2017 - nature.com
Although human epidemiological and genetic studies are essential to elucidate the
aetiology of normal and aberrant ocular development, animal models have provided us with …
aetiology of normal and aberrant ocular development, animal models have provided us with …
[HTML][HTML] How to plumb a pisces: understanding vascular development and disease using zebrafish embryos
BM Hogan, S Schulte-Merker - Developmental cell, 2017 - cell.com
Our vasculature plays diverse and critical roles in homeostasis and disease. In recent
decades, the use of zebrafish has driven our understanding of vascular development into …
decades, the use of zebrafish has driven our understanding of vascular development into …
Animal models of diabetic retinopathy: summary and comparison
AKW Lai, ACY Lo - Journal of diabetes research, 2013 - Wiley Online Library
Diabetic retinopathy (DR) is a microvascular complication associated with chronic exposure
to hyperglycemia and is a major cause of blindness worldwide. Although clinical …
to hyperglycemia and is a major cause of blindness worldwide. Although clinical …
Diabetic retinopathy: from animal models to cellular signaling
PM Pitale, MS Gorbatyuk - International Journal of Molecular Sciences, 2022 - mdpi.com
Diabetic retinopathy (DR) is an ocular complication of diabetes mellitus (DM), a metabolic
disorder characterized by elevation in blood glucose level. The pathogenesis of DR includes …
disorder characterized by elevation in blood glucose level. The pathogenesis of DR includes …
The visual system of zebrafish and its use to model human ocular diseases
Free swimming zebrafish larvae depend mainly on their sense of vision to evade predation
and to catch prey. Hence, there is strong selective pressure on the fast maturation of visual …
and to catch prey. Hence, there is strong selective pressure on the fast maturation of visual …
Hypoxia, angiogenesis, and metabolism in the hereditary kidney cancers
JC Chappell, LB Payne… - The Journal of clinical …, 2019 - Am Soc Clin Investig
The field of hereditary kidney cancer has begun to mature following the identification of
several germline syndromes that define genetic and molecular features of this cancer …
several germline syndromes that define genetic and molecular features of this cancer …
From oxygen to erythropoietin: relevance of hypoxia for retinal development, health and disease
C Caprara, C Grimm - Progress in retinal and eye research, 2012 - Elsevier
Photoreceptors and other cells of the retina consume large quantities of energy to efficiently
convert light information into a neuronal signal understandable by the brain. The necessary …
convert light information into a neuronal signal understandable by the brain. The necessary …