Schizophrenia (SCZ) and major depressive disorder (MDD) in treatment‐naive patients are
associated with increased risk for type 2 diabetes (T2D) and metabolic syndrome (MetS) …

The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …

Background Some studies have suggested that antipsychotic-naïve patients with
nonaffective psychosis (NAP) have glucose intolerance. Aims To conduct a systematic …

Mutations in HNF1A cause Maturity Onset Diabetes of the Young (HNF1A-MODY). To
understand mechanisms of β-cell dysfunction, we generated stem cell-derived pancreatic …

The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …

The increase in cardiovascular disease and reduced life expectancy in schizophrenia likely
relate to an increased prevalence of metabolic disturbances. Such metabolic risk factors in …

Aim To compare the differences of glucose metabolism outcomes between treatment‐naïve,
patients with first episode psychosis (FEP) and mood disorders. Methods We conducted a …

In this article the emerging biological overlaps of CNS disorders and psychiatric conditions
are reviewed. Recent work has highlighted how immune-inflammatory processes and their …

The GLIS family zinc finger 3 isoform (GLIS3) is a risk gene for Type 1 and Type 2 diabetes,
glaucoma and Alzheimer's disease endophenotype. We identified GLIS3 binding sites in …

Introduction Secure forensic mental health services are low volume, high cost services. They
offer care and treatment to mentally disordered offenders who pose a high risk of serious …