Abstract Context Although prostate cancer (PCa) screening reduces the incidence of
advanced disease and mortality, trade-offs include overdiagnosis and resultant …

A 12-core systematic biopsy that incorporates apical and far-lateral cores in the template
distribution allows maximal cancer detection, avoidance of a repeat biopsy while minimizing …

BACKGROUND: Accurate pretreatment assessment of prostate cancer (PCa)
aggressiveness is important in decision making. Gleason grade is a critical predictor of the …

PURPOSE: We evaluated the clinical usefulness of the PROGENSA® PCA3 Assay for
predicting repeat prostate biopsy outcome. MATERIALS AND METHODS: Men with at least …

Compatibility of mechatronic devices with the MR environment has been a very challenging
engineering task. After over a decade of developments, we report the successful translation …

We present an innovative approach allowing the identification, isolation, and molecular
characterization of disease-related exosomes based on their different antigenic reactivities …

Purpose: The objectives of this study were to 1) describe the patterns of repeat prostate
biopsy in men with a previous negative biopsy and 2) identify predictors of prostate cancer …

Background The diagnosis of prostate cancer is dependent on histologic confirmation in
biopsy core tissues. The biopsy procedure is invasive, puts the patient at risk for …

Objective To evaluate an epigenetic assay performed on tissue from negative prostate
biopsies in a group of African American (AA) men undergoing repeat biopsy, and to …

Background The diagnosis of prostate cancer involves invasive, sometimes harmful,
procedures that can entail negative quality-of-life implications to individuals and high …