Interruption of blood flow and gas exchange to the fetus in the perinatal period, known as
perinatal asphyxia, can, if significant, trigger a cascade of neuronal injury, leading on to …

Perinatal asphyxia (PA) is a burdening pathology with high short-term mortality and severe
long-term consequences. Its incidence, reaching as high as 10 cases per 1000 live births in …

Background Heart rate (HR) patterns can inform on central nervous system dysfunction. We
previously used highly comparative time series analysis (HCTSA) to identify HR patterns …

Heart rate variability (HRV) is currently considered the most valuable non-invasive test to
investigate the autonomic nervous system function, based on the fact that fast fluctuations …

Child health is defined by a complex, dynamic network of genetic, cultural, nutritional,
infectious, and environmental determinants at distinct, developmentally determined epochs …

Background Neonatal heart rate variability (HRV) is widely used as a research tool.
However, HRV calculation methods are highly variable making it difficult for comparisons …

Background Infants with mild HIE are at risk of significant disability at follow-up. In the pre-
therapeutic hypothermia (TH) era, electroencephalography (EEG) within 6 hours of birth was …

A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided.
During the past decades, the definition of HIE has evolved to accommodate the short …

Neonatal encephalopathy is a condition of disordered neonatal brain function and is
associated with many risk factors. The incidence of neonatal encephalopathy is estimated to …

Background Despite the increasing interest in fetal and neonatal heart rate variability (HRV)
analysis and its potential use as a tool for early disease stratification, no studies have …