Physical exercise and epigenetic modifications in skeletal muscle
Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …
known that regular exercise helps to lower the risk for a broad variety of health problems …
Exercise and GLUT4
M Flores-Opazo, SL McGee… - Exercise and sport …, 2020 - journals.lww.com
The glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to
insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the …
insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the …
Epigenetics and exercise
SL McGee, M Hargreaves - Trends in Endocrinology & Metabolism, 2019 - cell.com
Epigenetics can be defined as 'the structural adaptation of chromosomal regions so as to
register, signal, or perpetuate altered activity states.'Increased transcription of key regulatory …
register, signal, or perpetuate altered activity states.'Increased transcription of key regulatory …
SIRT6 widely regulates aging, immunity, and cancer
Y Li, J Jin, Y Wang - Frontiers in Oncology, 2022 - frontiersin.org
SIRT6 is a member of the Sir2-like family in mammals. Recent structural and biochemical
studies have characterized SIRT6 as having deacetylation, defatty-acylation, and mono-ADP …
studies have characterized SIRT6 as having deacetylation, defatty-acylation, and mono-ADP …
Impact of exercise and aging on mitochondrial homeostasis in skeletal muscle: roles of ROS and epigenetics
J Li, Z Wang, C Li, Y Song, Y Wang, H Bo, Y Zhang - Cells, 2022 - mdpi.com
Aging causes degenerative changes such as epigenetic changes and mitochondrial
dysfunction in skeletal muscle. Exercise can upregulate muscle mitochondrial homeostasis …
dysfunction in skeletal muscle. Exercise can upregulate muscle mitochondrial homeostasis …
Epigenetic modifications in pancreas development, diabetes, and therapeutics
Abstract A recent International Diabetes Federation report suggests that more than 463
million people between 20 and 79 years have diabetes. Of the 20 million women affected by …
million people between 20 and 79 years have diabetes. Of the 20 million women affected by …
High-intensity interval training remodels the proteome and acetylome of human skeletal muscle
M Hostrup, AK Lemminger, B Stocks… - Elife, 2022 - elifesciences.org
Exercise is an effective strategy in the prevention and treatment of metabolic diseases.
Alterations in the skeletal muscle proteome, including post-translational modifications …
Alterations in the skeletal muscle proteome, including post-translational modifications …
Adaptive responses of histone modifications to resistance exercise in human skeletal muscle
C Lim, J Shimizu, F Kawano, HJ Kim, CK Kim - PLoS One, 2020 - journals.plos.org
Exercise training causes epigenetic changes in skeletal muscle, although it is unclear how
resistance exercise (RE) affects histone modifications. The present study was carried out to …
resistance exercise (RE) affects histone modifications. The present study was carried out to …
[HTML][HTML] Myocyte enhancer factor 2A plays a central role in the regulatory networks of cellular physiopathology
B Liu, WC Ou, L Fang, CW Tian, Y Xiong - Aging and Disease, 2023 - ncbi.nlm.nih.gov
Cell regulatory networks are the determinants of cellular homeostasis. Any alteration to
these networks results in the disturbance of cellular homeostasis and induces cells towards …
these networks results in the disturbance of cellular homeostasis and induces cells towards …
The functions of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in diabetes progression
K Benchoula, A Mediani, WE Hwa - Journal of Cell Communication and …, 2023 - Springer
The increase in blood glucose causes a myriad of pathways and molecular components to
malfunction, leading to diabetes. Diabetes affects each organ differently by activating distinct …
malfunction, leading to diabetes. Diabetes affects each organ differently by activating distinct …