Locoregional therapies in the era of molecular and immune treatments for hepatocellular carcinoma

JM Llovet, T De Baere, L Kulik, PK Haber… - Nature reviews …, 2021 - nature.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality and
has an increasing incidence worldwide. Locoregional therapies, defined as imaging-guided …

Recent updates of transarterial chemoembolilzation in hepatocellular carcinoma

Y Chang, SW Jeong, J Young Jang… - International journal of …, 2020 - mdpi.com
Transarterial chemoembolization (TACE) is a standard treatment for intermediate-stage
hepatocellular carcinoma (HCC). In this review, we summarize recent updates on the use of …

Standard for diagnosis and treatment of primary liver cancer (2022 edition)

General Office of National Health Commission - 临床肝胆病杂志, 2022 - lcgdbzz.org
Standard for diagnosis and treatment of primary liver cancer (2022 edition) 中文|English ISSN
1001-5256 (Print) ISSN 2097-3497 (Online) CN 22-1108/R Home About Journal 1.Journal …

[HTML][HTML] A review of 2022 Chinese clinical guidelines on the management of hepatocellular carcinoma: updates and insights

DY Xie, K Zhu, ZG Ren, J Zhou, J Fan… - … Surgery and Nutrition, 2023 - ncbi.nlm.nih.gov
Significant improvements in the management of hepatocellular carcinoma (HCC) during the
past three years have urged the timely update of clinical guidelines in China. In brief, aMAP …

Randomized phase 3 LEAP-012 study: transarterial chemoembolization with or without lenvatinib plus pembrolizumab for intermediate-stage hepatocellular …

JM Llovet, A Vogel, DC Madoff, RS Finn… - Cardiovascular and …, 2022 - Springer
Purpose Transarterial chemoembolization (TACE) is the standard of care for patients with
intermediate-stage hepatocellular carcinoma (HCC). Lenvatinib, a multikinase inhibitor, and …

Current strategies for the treatment of intermediate and advanced hepatocellular carcinoma

A Vogel, A Saborowski - Cancer treatment reviews, 2020 - Elsevier
Hepatocellular carcinoma (HCC) ranks among the most common cancers worldwide and
remains to be a major global health care problem. Until 2007, no effective therapies were …

Lenvatinib plus TACE with or without pembrolizumab for the treatment of initially unresectable hepatocellular carcinoma harbouring PD-L1 expression: a retrospective …

S Chen, Z Wu, F Shi, Q Mai, L Wang, F Wang… - Journal of Cancer …, 2022 - Springer
Purpose The aim of this retrospective study was to compare the clinical outcomes of
pembrolizumab-lenvatinib-transarterial chemoembolization (TACE) versus lenvatinib-TACE …

Clinical-radiomic analysis for pretreatment prediction of objective response to first transarterial chemoembolization in hepatocellular carcinoma

M Chen, J Cao, J Hu, W Topatana, S Li, S Juengpanich… - Liver Cancer, 2021 - karger.com
Background: The preoperative selection of patients with intermediate-stage hepatocellular
carcinoma (HCC) who are likely to have an objective response to first transarterial …

Local and regional therapies for hepatocellular carcinoma

R Kloeckner, PR Galle, J Bruix - Hepatology, 2021 - Wiley Online Library
Local and regional therapies are recommended for patients with hepatocellular carcinoma
(HCC) in very early (Barcelona Clinic Liver Cancer [BCLC] 0), early (BCLC A), and …

The importance of liver functional reserve in the non-surgical treatment of hepatocellular carcinoma

D D'Avola, A Granito, M De La Torre-Alaez… - Journal of …, 2022 - Elsevier
The aim of any oncological treatment is not just to eliminate the tumour, but to maximise
patient survival and quality of life. Since the liver has a vital function, any radical treatment …