Corneal wound healing is a complex process involving cell death, migration, proliferation,
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …

Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

Purpose.: The present study was designed to understand the role of inflammatory cytokines
secreted by corneal epithelial cells in keratoconus (KC) and the response to treatment with …

Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-
inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently …

Corneal scarring is a leading cause of worldwide blindness. Human mesenchymal stem
cells (MSC) have been reported to promote corneal wound healing through secreted …

Inflammation induced by lung infection is a double-edged sword, moderating both anti-viral
and immune pathogenesis effects; the mechanism of the latter is not fully understood …

Background Trachoma causes blindness through a conjunctival scarring process initiated by
ocular Chlamydia trachomatis infection; however, the rates, drivers and pathophysiological …

Purpose: To evaluate the safety and feasibility of intrastromal injection of human corneal
stromal keratocytes (CSKs) and its therapeutic effect on a rodent early corneal opacity …

Intrastromal cell therapy utilizing quiescent corneal stromal keratocytes (qCSKs) from human
donor corneas emerges as a promising treatment for corneal opacities, aiming to overcome …

Corneal dystrophies are phenotypically and genetically heterogeneous, often resulting in
visual impairment caused by corneal opacification. We investigated the genetic cause of an …