Epidemiology of neuromyelitis optica spectrum disorder and its prevalence and incidence worldwide

JY Hor, N Asgari, I Nakashima, SA Broadley… - Frontiers in …, 2020 - frontiersin.org
Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon inflammatory disease of
the central nervous system, manifesting clinically as optic neuritis, myelitis, and certain brain …

Diagnosis of multiple sclerosis: progress and challenges

WJ Brownlee, TA Hardy, F Fazekas, DH Miller - The Lancet, 2017 - thelancet.com
The diagnosis of multiple sclerosis is based on neurological symptoms and signs, alongside
evidence of dissemination of CNS lesions in space and time. MRI is often sufficient to …

[HTML][HTML] Trial of satralizumab in neuromyelitis optica spectrum disorder

T Yamamura, I Kleiter, K Fujihara… - … England Journal of …, 2019 - Mass Medical Soc
Background Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disease of
the central nervous system and is associated with autoantibodies to anti–aquaporin-4 …

Clinical presentation and prognosis in MOG-antibody disease: a UK study

M Jurynczyk, S Messina, MR Woodhall, N Raza… - Brain, 2017 - academic.oup.com
Abstract See de Seze (doi: 10.1093/brain/awx292) for a scientific commentary on this article.
A condition associated with an autoantibody against MOG has been recently recognized as …

B cells in autoimmune and neurodegenerative central nervous system diseases

JJ Sabatino Jr, AK Pröbstel, SS Zamvil - Nature Reviews Neuroscience, 2019 - nature.com
B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology

K Fujihara, JL Bennett, J de Seze… - Neurology …, 2020 - AAN Enterprises
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that
preferentially affects the spinal cord and optic nerve. Most patients with NMOSD experience …

Hope for patients with neuromyelitis optica spectrum disorders—from mechanisms to trials

SJ Pittock, A Zekeridou, BG Weinshenker - Nature Reviews Neurology, 2021 - nature.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

Classification, diagnosis, and differential diagnosis of multiple sclerosis

IK Sand - Current opinion in neurology, 2015 - journals.lww.com
Current multiple sclerosis phenotypic classifications include relapsing-remitting multiple
sclerosis, clinically isolated syndrome, radiologically isolated syndrome, primary …

Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS)

C Trebst, S Jarius, A Berthele, F Paul, S Schippling… - Journal of …, 2014 - Springer
Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis

S Ramanathan, K Prelog, EH Barnes… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Recognizing the cause of optic neuritis (ON) affects treatment decisions and
visual outcomes. Objective: We aimed to define radiological features of first-episode …