Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Osteonecrosis of the femoral head (ONFH) is a devastating and complicated disease with an
unclear etiology. Femoral head‐preserving surgeries have been devoted to delaying and …

Intracellular delivery of advanced therapeutics, including biologicals and supramolecular
agents, is complex because of the natural biological barriers that have evolved to protect the …

Gene editing is a versatile technique in biomedicine that promotes fundamental research as
well as clinical therapy. The development of Clustered Regularly Interspaced Short …

Three-dimensional vertical micro-and nanostructures can enhance the signal quality of
multielectrode arrays and promise to become the prime methodology for the investigation of …

Allosteric transitions can modulate the self‐assembly and biological function of proteins. It
remains, however, tremendously challenging to design synthetic allosteric polymeric …

The start-ups taking nanoneedles into the clinic | Nature Nanotechnology Skip to main content
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Background Nanoinjection—the process of intracellular delivery using vertically configured
nanostructures—is a physical route that efficiently negotiates the plasma membrane, with …

Surface‐enhanced Raman spectroscopy (SERS) has become a sensitive detection
technique for biochemical analysis. Despite significant research efforts, most SERS …