Liquid biopsy for lung cancer: up-to-date and perspectives for screening programs
GMS Casagrande, MO Silva, RM Reis… - International Journal of …, 2023 - mdpi.com
Lung cancer is the deadliest cancer worldwide. Tissue biopsy is currently employed for the
diagnosis and molecular stratification of lung cancer. Liquid biopsy is a minimally invasive …
diagnosis and molecular stratification of lung cancer. Liquid biopsy is a minimally invasive …
Autoantibodies: opportunities for early cancer detection
Cancer cells can induce an immunological response resulting in the production of tumor-
associated (TA) autoantibodies. These serum immunobiomarkers have been detected for a …
associated (TA) autoantibodies. These serum immunobiomarkers have been detected for a …
EarlyCDT®-Lung test: improved clinical utility through additional autoantibody assays
CJ Chapman, GF Healey, A Murray, P Boyle… - Tumor Biology, 2012 - Springer
Tumor-associated autoantibodies (AAbs) have been described in patients with lung cancer,
and the Early CDT®-Lung test that measures such AAbs is available as an aid for the early …
and the Early CDT®-Lung test that measures such AAbs is available as an aid for the early …
[HTML][HTML] Clinical validation of an autoantibody test for lung cancer
P Boyle, CJ Chapman, S Holdenrieder, A Murray… - Annals of …, 2011 - Elsevier
Background Autoantibodies may be present in a variety of underlying cancers several years
before tumours can be detected and testing for their presence may allow earlier diagnosis …
before tumours can be detected and testing for their presence may allow earlier diagnosis …
[HTML][HTML] Audit of the autoantibody test, EarlyCDT®-lung, in 1600 patients: an evaluation of its performance in routine clinical practice
JR Jett, LJ Peek, L Fredericks, W Jewell, WW Pingleton… - Lung cancer, 2014 - Elsevier
Abstract Objectives EarlyCDT®-Lung may enhance detection of early stage lung cancer by
aiding physicians in assessing high-risk patients through measurement of biological …
aiding physicians in assessing high-risk patients through measurement of biological …
EarlyCDT-Lung: An Immunobiomarker Test as an Aid to Early Detection of Lung Cancer
S Lam, P Boyle, GF Healey, P Maddison, L Peek… - Cancer prevention …, 2011 - AACR
Recent publications have reported the technical and clinical validation of Early CDT-Lung,
an autoantibody test which detected elevated autoantibodies in 40% of lung cancers at …
an autoantibody test which detected elevated autoantibodies in 40% of lung cancers at …
Performance of a multiplexed dual analyte immunoassay for the early detection of non-small cell lung cancer
V Doseeva, T Colpitts, G Gao, J Woodcock… - Journal of translational …, 2015 - Springer
Abstract Objectives “PAULA's” test (P rotein A ssays U tilizing L ung cancer A nalytes) is a
novel multiplex immunoassay blood test that incorporates both tumor antigens and …
novel multiplex immunoassay blood test that incorporates both tumor antigens and …
Serum tumor-associated autoantibodies as diagnostic biomarkers for lung cancer: A systematic review and meta-analysis
ZM Tang, ZG Ling, CM Wang, YB Wu, JL Kong - PLoS One, 2017 - journals.plos.org
Objective We performed a comprehensive review and meta-analysis to evaluate the
diagnostic values of serum single and multiplex tumor-associated autoantibodies (TAAbs) in …
diagnostic values of serum single and multiplex tumor-associated autoantibodies (TAAbs) in …
[HTML][HTML] Autoantibody signature enhances the positive predictive power of computed tomography and nodule-based risk models for detection of lung cancer
PP Massion, GF Healey, LJ Peek, L Fredericks… - Journal of Thoracic …, 2017 - Elsevier
Introduction The incidence of pulmonary nodules is increasing with the movement toward
screening for lung cancer by low-dose computed tomography. Given the large number of …
screening for lung cancer by low-dose computed tomography. Given the large number of …
Long-term survival in paraneoplastic Lambert-Eaton myasthenic syndrome
P Maddison, P Gozzard, MJ Grainge, B Lang - Neurology, 2017 - AAN Enterprises
Objective: To establish whether improved tumor survival in patients with Lambert-Eaton
myasthenic syndrome (LEMS) and small-cell lung cancer (SCLC) was due to known …
myasthenic syndrome (LEMS) and small-cell lung cancer (SCLC) was due to known …