Proton channels exist in a wide variety of membrane proteins where they transport protons
rapidly and efficiently. Usually the proton pathway is formed mainly by water molecules …

Voltage-gated proton channels (HV) are unique, in part because the ion they conduct is
unique. HV channels are perfectly selective for protons and have a very small unitary …

Objective In the majority of patients with rheumatoid arthritis (RA), antibodies specifically
recognize citrullinated autoantigens that are generated by peptidylarginine deiminases …

On activation of human basophilic granulocytes with anti-IgE or with the chemotactic
peptide, formyl-methionyl-leucyl-phenylalanine, the expression of the CD63 antigen on the …

Mitochondria are known to combine life-supporting functions with participation in apoptosis
by controlling caspase activity. Here, we report that in human blood neutrophils the …

Background A number of allergenic proteins in peanut has been described and the relative
importance of these allergens is yet to be determined. Objectives We have investigated the …

Basophils are primarily associated with a proinflammatory and immunoregulatory role in
allergic diseases and parasitic infections. Recent studies have shown that basophils can …

Tyrosine phosphorylation is an important regulatory mechanism in response to the action of
growth factors and oncogenes. Since many oncogenes code for tyrosine kinases, increased …

A monoclonal antibody and an affinity purified polyclonal antibody, both raised against
recombinant human IL-6, have been employed in an ELISA procedure to quantitate human …

Harnessing neutrophils for the eradication of cancer cells remains an attractive but still
controversial notion. In this study, we provide evidence that neutrophils are required to …