Lipid droplets (LDs) are dynamic, cytosolic lipid‐storage organelles found in nearly all cell
types. Too many or too few LDs during excess or deficient fat storage lead to many different …

The heart is a rhythmic electromechanical pump, the functioning of which depends on action
potential generation and propagation, followed by relaxation and a period of refractoriness …

Nonstandard abbreviations used: glycophosphatidylinositolanchored (GPI-anchored);
endothelial nitric oxide synthase (eNOS); β-secretase (BACE); endoplasmic reticulum (ER); …

Congenital generalized lipodystrophy (CGL) is a heterogeneous autosomal recessive
disorder characterized by a near complete lack of adipose tissue from birth and, later in life …

Lipid uptake and metabolism are central to the function of organs such as heart, skeletal
muscle, and adipose tissue. Although most heart energy derives from fatty acids (FAs) …

The caveolin gene family has three members in vertebrates: caveolin-1, caveolin-2, and
caveolin-3. So far, most caveolin-related research has been conducted in mammals, but the …

The fibrotic diseases encompass a wide spectrum of entities including such multisystemic
diseases as systemic sclerosis, nephrogenic systemic fibrosis and sclerodermatous graft …

The many components of G‐protein‐coupled receptor (GPCR) signal transduction provide
cells with numerous combinations with which to customize their responses to hormones …

Caveolae, flask-like invaginations of the plasma membrane, were discovered nearly 60
years ago. Originally regarded as fixation artifacts of electron microscopy, the functional role …

Caveolae are specialized membrane microdomains present within the plasma membrane of
the vast majority of cell types. They have a unique composition in that they are highly …