Recent advances in type I organic photosensitizers for efficient photodynamic therapy for overcoming tumor hypoxia

B Lu, L Wang, H Tang, D Cao - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Photodynamic therapy (PDT) with an oxygen-dependent character is a noninvasive
therapeutic method for cancer treatment. However, its clinical therapeutic effect is greatly …

Optimized strategies of ROS-based nanodynamic therapies for tumor theranostics

Y Di, R Deng, Z Liu, Y Mao, Y Gao, Q Zhao, S Wang - Biomaterials, 2023 - Elsevier
Reactive oxygen species (ROS) play a crucial role in regulating the metabolism of tumor
growth, metastasis, death and other biological processes. ROS-based nanodynamic …

A Self‐Enhancing Nanoreactor Reinforces Radioimmunotherapy by Reprogramming Nutrients and Redox Metabolisms

M Hou, H Su, Q Wu, W Sun, P Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Altered metabolism of cancer cells reshapes the unique tumor microenvironment (TME) with
glucose addiction and high antioxidant levels, resulting in a strong alliance to promote tumor …

Designing temporal-and spatial-control multifunctional nanoformulations for synergistic photodynamic–enhanced tumour immunotherapy

P Zhang, Y Cui, Y Wang - Nano Today, 2023 - Elsevier
The combination of light-activated therapy and immunotherapy is attracting considerable
attention in tumour therapy. However, increasing the safety, quality, and durability of light …

Efficient type Ⅰ and type Ⅱ ROS generated aggregation-induced emission photosensitizer for mitochondria targeted photodynamic therapy

Y Xiao, Y Yuan, M Liang, J Ni, L Yu, ZS Huang, B Du… - Dyes and …, 2023 - Elsevier
Fluorescence imaging-guided photodynamic therapy (PDT) is considered as an ideal
alternative strategy to treat tumors. However, insufficient supply of oxygen in solid tumor …

A targeted phototheranostic agent with strong AIE effect and boosted type I ROS generation

Y Wang, C Zhang, Y Li, R Li, J Li, L Feng - Dyes and Pigments, 2023 - Elsevier
Hypoxia and nonspecific killing always hinder the photodynamic therapy of malignant
tumors and infectious diseases that both severely threatening human health. Herein, we …

Recent Advances in the Enzyme‐Activatable Organic Fluorescent Probes for Tumor Imaging and Therapy

SB Lu, L Wei, W He, ZY Bi, Y Qian, J Wang… - …, 2022 - Wiley Online Library
The exploration of advanced probes for cancer diagnosis and treatment is of high
importance in fundamental research and clinical practice. In comparison with the traditional …

[HTML][HTML] Single aromatics sulfonamide substituted dibenzothiazole squaraines for tumor NIR imaging and efficient photodynamic therapy at low drug dose

JH Li, PD You, F Lu, JT Huang, JL Fu, HY Tang… - … of Photochemistry and …, 2023 - Elsevier
On the base of the zwiterionic dibenzothiazole squaraine SQ, five cationic aromatics
sulfonamide substituted dibenzothiazole squaraines SQ-D1∼ 5 have been designed and …

Triphenylamine-AIEgens photoactive materials for cancer theranostics

J Wang, Y Wang, Z Li, C Xie, M Khan, X Peng… - Chinese Chemical …, 2024 - Elsevier
Abstract Triphenylamine (TPA)-based aggregation-induced emission luminogens (TPA-
AIEgens), a type of photoactive material utilizing the typical TPA moiety, has recently …

Nanocarrier-Mediated Immunogenic Cell Death for Melanoma Treatment

J Wang, J Ma, Z Tai, L Li, T Zhang… - International Journal …, 2023 - Taylor & Francis
Melanoma, a highly aggressive skin tumor, exhibits notable features including
heterogeneity, a high mutational load, and innate immune escape. Despite advancements in …