The altered metabolic programme of cancer cells facilitates their cell-autonomous
proliferation and survival. In normal cells, signal transduction pathways control core cellular …

Reprogramming of lipid metabolism is a newly recognized hallmark of malignancy.
Increased lipid uptake, storage and lipogenesis occur in a variety of cancers and contribute …

The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …

Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …

Cancer cells employ both conventional oxidative metabolism and glycolytic anaerobic
metabolism. However, their proliferation is marked by a shift towards increasing glycolytic …

Lipid metabolic reprogramming plays a pivotal role in hepatocellular carcinoma (HCC)
development, but the underlying mechanisms are incompletely characterized. Long chain …

Oral cancer (OC) is a devastating disease that takes the lives of lots of people globally every
year. The current spectrum of treatment modalities does not meet the needs of the patients …

ACLY links energy metabolism provided by catabolic pathways to biosynthesis. ACLY,
which has been found to be overexpressed in many cancers, converts citrate into acetyl-CoA …

Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and is
vital to various normal biological functions. It is a key factor in lifestyle-related diseases …

ATP citrate lyase (ACLY) is a cytosolic homotetrameric enzyme that catalyzes the conversion
of citrate and coenzyme A (CoA) to acetyl-CoA and oxaloacetate, with the simultaneous …