[HTML][HTML] Superoxide anion chemistry—Its role at the core of the innate immunity

CMC Andrés, JM Pérez de la Lastra… - International journal of …, 2023 - mdpi.com
Classically, superoxide anion O2•− and reactive oxygen species ROS play a dual role. At
the physiological balance level, they are a by-product of O2 reduction, necessary for cell …

[HTML][HTML] Chemical basis of reactive oxygen species reactivity and involvement in neurodegenerative diseases

F Collin - International journal of molecular sciences, 2019 - mdpi.com
Increasing numbers of individuals suffer from neurodegenerative diseases, which are
characterized by progressive loss of neurons. Oxidative stress, in particular, the …

[HTML][HTML] Antioxidative properties of phenolic compounds and their effect on oxidative stress induced by severe physical exercise

J Kruk, BH Aboul-Enein, E Duchnik… - The Journal of …, 2022 - Springer
Extensive research has found strongly increased generation of reactive oxygen species, free
radicals, and reactive nitrogen species during acute physical exercise that can lead to …

Raman spectroscopy in cell biology and microbiology

G Pezzotti - Journal of Raman Spectroscopy, 2021 - Wiley Online Library
The Raman spectrum of living cells and microorganisms contains highly specific fingerprint‐
like signatures, useful in unequivocally identifying different species and interpreting …

Hypertension and aging

TW Buford - Ageing research reviews, 2016 - Elsevier
Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

Melatonin as a natural ally against oxidative stress: a physicochemical examination

A Galano, DX Tan, RJ Reiter - Journal of pineal research, 2011 - Wiley Online Library
Oxidative stress has been proven to be related to the onset of a large number of health
disorders. This chemical stress is triggered by an excess of free radicals, which are …

[HTML][HTML] A review of the antioxidant mechanisms of polyphenol compounds related to iron binding

NR Perron, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
In this review, primary attention is given to the antioxidant (and prooxidant) activity of
polyphenols arising from their interactions with iron both in vitro and in vivo. In addition, an …

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

S Nagaraj, K Gupta, V Pisarev, L Kinarsky… - Nature medicine, 2007 - nature.com
Abstract Antigen-specific CD8+ T-cell tolerance, induced by myeloid-derived suppressor
cells (MDSCs), is one of the main mechanisms of tumor escape. Using in vivo models, we …

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1–dependent mechanism that is up-regulated by …

SL Highfill, PC Rodriguez, Q Zhou… - Blood, The Journal …, 2010 - ashpublications.org
Myeloid-derived suppressor cells (MDSCs) are a well-defined population of cells that
accumulate in the tissue of tumor-bearing animals and are known to inhibit immune …

Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide

GL Squadrito, WA Pryor - Free Radical Biology and Medicine, 1998 - Elsevier
The roles of superoxide (O2•−), peroxynitrite, and carbon dioxide in the oxidative chemistry
of nitric oxide (NO) are reviewed. The formation of peroxynitrite from NO and O2•− is …