Iron metabolism: an emerging therapeutic target in critical illness
E Litton, J Lim - Annual Update in Intensive Care and Emergency …, 2019 - Springer
Iron is required for erythropoiesis and is also essential for many other life-sustaining
functions including deoxyribonucleic acid (DNA) and neurotransmitter synthesis …
functions including deoxyribonucleic acid (DNA) and neurotransmitter synthesis …
[HTML][HTML] Iron administration, infection, and anemia management in CKD: untangling the effects of intravenous iron therapy on immunity and infection risk
T Ganz, GR Aronoff, CAJM Gaillard, LT Goodnough… - Kidney Medicine, 2020 - Elsevier
Patients with chronic kidney disease (CKD) are at increased risk for infection, attributable to
immune dysfunction, increased exposure to infectious agents, loss of cutaneous barriers …
immune dysfunction, increased exposure to infectious agents, loss of cutaneous barriers …
Association between iron status and the risk of adverse outcomes in COVID-19
Y Lv, L Chen, X Liang, X Liu, M Gao, Q Wang, Q Wei… - Clinical Nutrition, 2021 - Elsevier
Background & aims Iron is an essential trace element to almost all organism, and the
delicate balance between host defend system and viral proliferation plays an important role …
delicate balance between host defend system and viral proliferation plays an important role …
Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
RM Mohus, H Flatby, KV Liyanarachi, AT DeWan… - Scientific Reports, 2022 - nature.com
Observational studies have indicated an association between iron status and risk of sepsis
and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of …
and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of …
[HTML][HTML] Role of reactive oxygen species and iron in host defense against infection
KB Dickson, J Zhou - Frontiers in Bioscience-Landmark, 2020 - imrpress.com
Reactive oxygen species (ROS) and iron play important roles in the innate immune
response. ROS are released by immune cells and are highly reactive and indiscriminately …
response. ROS are released by immune cells and are highly reactive and indiscriminately …
Iron status and NAFLD among European populations: A bidirectional two-sample Mendelian randomization study
C Liu, Y Chen, Z Zhang, J Xie, C Yu, L Xu, Y Li - Nutrients, 2022 - mdpi.com
Background and aim: Previous observational studies have suggested a paradoxical
relationship between iron status and the risk of non-alcoholic fatty liver disease (NAFLD) …
relationship between iron status and the risk of non-alcoholic fatty liver disease (NAFLD) …
Population-based risk factors for community-onset bloodstream infections
KB Laupland, K Pasquill, G Dagasso, EC Parfitt… - European Journal of …, 2020 - Springer
Although a number of comorbidities have been associated with development of bloodstream
infection, actual risk factors have not been well defined and quantified in nonselected …
infection, actual risk factors have not been well defined and quantified in nonselected …
Causal associations of iron status with gout and rheumatoid arthritis, but not with inflammatory bowel disease
Background & aims We conducted a two-sample Mendelian randomization study to assess
the associations of iron homeostasis with the risk of gout, rheumatoid arthritis and …
the associations of iron homeostasis with the risk of gout, rheumatoid arthritis and …
Iron, hemochromatosis genotypes, and risk of infections: a cohort study of 142 188 general population individuals
M Mottelson, A Glenthøj, BG Nordestgaard, C Ellervik… - Blood, 2024 - ashpublications.org
It is unclear whether risk of infection is increased in individuals with hereditary
hemochromatosis and in individuals with low or high plasma iron, transferrin saturation, or …
hemochromatosis and in individuals with low or high plasma iron, transferrin saturation, or …
Associations between pre‐operative iron deficiency and postoperative infection in patients undergoing major surgery (CARIPO): a prospective observational study
M Campfort, T Perrault, A Blanchard‐Daguet… - …, 2024 - Wiley Online Library
Introduction Iron deficiency, with or without anaemia, is common during the peri‐operative
period. It has been hypothesised that pre‐operative iron deficiency is associated with an …
period. It has been hypothesised that pre‐operative iron deficiency is associated with an …