Abstract The ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) …

Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Background The β-lactamase inhibitor relebactam can restore imipenem activity against
imipenem-nonsusceptible gram-negative pathogens. We evaluated imipenem/relebactam …

Abstract Objectives Infections caused by Klebsiella pneumoniae (Kp) carbapenemase
(KPC)-producing strains of Kp have become a significant threat in recent years. To assess …

Healthcare‐associated infections due to multidrug‐resistant Gram‐negative bacteria (MDR‐
GNB) are a leading cause of morbidity and mortality worldwide. These evidence‐based …

Carbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) are currently among
the most important nosocomial pathogens. An observational study was conducted during …

This article provides a comprehensive review of currently available treatment options for
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …

This study quantified mortality associated with serious infections caused by carbapenem-
resistant (CRE) and carbapenem-susceptible Enterobacteriaceae (CSE). A systematic …

Abstract Knowledge of carbapenem‐resistant Klebsiella pneumoniae (CR‐KP) colonization
is important to prevent nosocomial spread but also to start prompt adequate antibiotic …

Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense
against multidrug‐resistant Gram‐negative organisms. Over the last decade, carbapenem …