HOTAIR LncRNA: a novel oncogenic propellant in human cancer

T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …

Role of HOX genes in stem cell differentiation and cancer

S Bhatlekar, JZ Fields, BM Boman - Stem cells international, 2018 - Wiley Online Library
HOX genes encode an evolutionarily conserved set of transcription factors that control how
the phenotype of an organism becomes organized during development based on its genetic …

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma

H Kocak, S Ackermann, B Hero, Y Kahlert… - Cell death & …, 2013 - nature.com
Neuroblastoma is an embryonal malignancy of the sympathetic nervous system.
Spontaneous regression and differentiation of neuroblastoma is observed in a subset of …

miR‐224 promotion of cell migration and invasion by targeting Homeobox D 10 gene in human hepatocellular carcinoma

Q Li, C Ding, C Chen, Z Zhang, H Xiao… - Journal of …, 2014 - Wiley Online Library
Abstract Background and Aim Micro RNA s (mi RNA s) are small noncoding RNA molecules
that control target gene expression and are implicated in the regulation of diverse cellular …

Significance of HOXD transcription factors family in progression, migration and angiogenesis of cancer

L Wang, C Qiao, L Cao, S Cai, X Ma, X Song… - Critical Reviews in …, 2022 - Elsevier
The transcription factors (TFs) of the HOX family play significant roles during early embryonic
development and cellular processes. They also play a key role in tumorigenesis as tumor …

Dynamic regulation of BDNF gene expression by estradiol and lncRNA HOTAIR

P Deb, A Chini, P Guha, A Rishi, A Bhan, B Brady… - Gene, 2024 - Elsevier
Brain derived neurotrophic factor (BDNF) is a major neurotransmitter that controls growth
and maintenance of neurons and its misregulation is linked to neurodegeneration and …

HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer

MA Mansour, T Senga - The international journal of biochemistry & cell …, 2017 - Elsevier
Homeobox (HOX) genes are conserved transcription factors which determine the anterior-
posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several …

3′ LIFE: a functional assay to detect miRNA targets in high-throughput

JM Wolter, K Kotagama, AC Pierre-Bez… - Nucleic acids …, 2014 - academic.oup.com
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene output at the post-
transcriptional level by targeting degenerate elements primarily in 3′ untranslated regions …

Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

L Yang, Y Zha, J Ding, B Ye, M Liu, C Yan, Z Dong… - Oncogenesis, 2019 - nature.com
Induction of differentiation is a therapeutic strategy in high-risk neuroblastoma, a childhood
cancer of the sympathetic nervous system. Neuroblastoma differentiation requires …

Temporal multiplexing of perception and memory codes in IT cortex

L She, MK Benna, Y Shi, S Fusi, DY Tsao - Nature, 2024 - nature.com
A central assumption of neuroscience is that long-term memories are represented by the
same brain areas that encode sensory stimuli. Neurons in inferotemporal (IT) cortex …