How and when should we monitor chimerism after allogeneic stem cell transplantation?

P Bader, D Niethammer, A Willasch… - Bone marrow …, 2005 - nature.com
Chimerism analysis has become an important tool for the peri-transplant surveillance of
engraftment. It offers the possibility to realize impending graft rejection and can serve as an …

A practical guide to chimerism analysis: review of the literature and testing practices worldwide

AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease

O Ringdén, M Uzunel, I Rasmusson… - …, 2006 - journals.lww.com
Background. Mesenchymal stem cells (MSC) have immunomodulatory effects. The aim was
to study the effect of MSC infusion on graft-versus-host disease (GVHD). Methods. We gave …

Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells

K Le Blanc, H Samuelsson, B Gustafsson… - Leukemia, 2007 - nature.com
Seven patients underwent treatment with mesenchymal stem cells (MSCs), together with
allogeneic hematopoietic stem cell transplantation (HSCT). MSCs were given to three …

Reduced intensity conditioning compared with myeloablative conditioning using unrelated donor transplants in patients with acute myeloid leukemia

O Ringdén, M Labopin, G Ehninger… - Journal of Clinical …, 2009 - ascopubs.org
Purpose Reduced intensity conditioning regimen (RIC) is increasingly used in
hematopoietic stem cell transplantation (HSCT). Unrelated donor (UD) transplants have …

The allogeneic graft‐versus‐cancer effect

O Ringdén, H Karlsson, R Olsson… - British journal of …, 2009 - Wiley Online Library
Allogeneic haematological stem cell transplantation (HSCT) has developed into
immunotherapy. Donor CD4+, CD8+ and natural killer (NK) cells have been reported to …

Immunosuppressive CD14+ HLA-DRlow/neg IDO+ myeloid cells in patients following allogeneic hematopoietic stem cell transplantation

D Mougiakakos, R Jitschin, L Von Bahr, I Poschke… - Leukemia, 2013 - nature.com
Myeloid-derived suppressor cells (MDSCs) have emerged as a heterogeneic
immunoregulatory population that can expand in response to inflammatory signals …

[HTML][HTML] Monitoring of donor chimerism in sorted CD34+ peripheral blood cells allows the sensitive detection of imminent relapse after allogeneic stem cell …

M Bornhäuser, U Oelschlaegel, U Platzbecker… - …, 2009 - ncbi.nlm.nih.gov
Abstract Analysis of donor chimerism is an important diagnostic tool to assess the risk of
relapse after allogeneic stem cell transplantation, especially in patients lacking a specific …

[HTML][HTML] NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the …

SZ Pavletic, S Kumar, M Mohty, M de Lima… - Biology of Blood and …, 2010 - Elsevier
Allogeneic hematopoietic stem cell transplantation (alloHSCT) is increasingly being used for
treatment of hematologic malignancies, and the immunologic graft-versus-tumor effect (GVT) …

Transplanted bone marrow-derived cells contribute to human adipogenesis

M Ryden, M Uzunel, JL Hård, E Borgström, JE Mold… - Cell metabolism, 2015 - cell.com
Because human white adipocytes display a high turnover throughout adulthood, a
continuous supply of precursor cells is required to maintain adipogenesis. Bone marrow …