Functional relationship between osteogenesis and angiogenesis in tissue regeneration
F Diomede, GD Marconi, L Fonticoli… - International Journal of …, 2020 - mdpi.com
Bone tissue renewal can be outlined as a complicated mechanism centered on the
interaction between osteogenic and angiogenic events capable of leading to bone formation …
interaction between osteogenic and angiogenic events capable of leading to bone formation …
A road map for understanding molecular and genetic determinants of osteoporosis
Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …
Mesenchymal stem cells: cell fate decision to osteoblast or adipocyte and application in osteoporosis treatment
L Hu, C Yin, F Zhao, A Ali, J Ma, A Qian - International Journal of …, 2018 - mdpi.com
Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …
degraded bone microstructure, which leads to increased bone fragility and risks of bone …
Osteoblast differentiation and signaling: established concepts and emerging topics
M Ponzetti, N Rucci - International Journal of Molecular Sciences, 2021 - mdpi.com
Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation
Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a
fundamental role in the regulation of bone organogenesis through the activation of receptor …
fundamental role in the regulation of bone organogenesis through the activation of receptor …
Senile osteoporosis: the involvement of differentiation and senescence of bone marrow stromal cells
A Qadir, S Liang, Z Wu, Z Chen, L Hu… - International journal of …, 2020 - mdpi.com
Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …
population. It increases the risk of bone fracture and seriously affects human health. Unlike …
Adipose‐derived stem cells for tissue engineering and regenerative medicine applications
Adipose‐derived stem cells (ASCs) are a mesenchymal stem cell source with properties of
self‐renewal and multipotential differentiation. Compared to bone marrow‐derived stem …
self‐renewal and multipotential differentiation. Compared to bone marrow‐derived stem …
Development of micro RNA therapeutics is coming of age
E Van Rooij, S Kauppinen - EMBO molecular medicine, 2014 - embopress.org
Micro RNA s (mi RNA s) play key regulatory roles in diverse biological processes and are
frequently dysregulated in human diseases. Thus, mi RNA s have emerged as a class of …
frequently dysregulated in human diseases. Thus, mi RNA s have emerged as a class of …
miR-214 targets ATF4 to inhibit bone formation
Emerging evidence indicates that microRNAs (miRNAs) have important roles in regulating
osteogenic differentiation and bone formation. Thus far, no study has established the …
osteogenic differentiation and bone formation. Thus far, no study has established the …