Retrieval-extinction and relapse prevention: rewriting maladaptive drug memories?
Addicted individuals are highly susceptible to relapse when exposed to drug-associated
conditioned stimuli (CSs;“drug cues”) even after extensive periods of abstinence. Until …
conditioned stimuli (CSs;“drug cues”) even after extensive periods of abstinence. Until …
Cross-talk between the HPA axis and addiction-related regions in stressful situations
M Nikbakhtzadeh, H Ranjbar, K Moradbeygi, E Zahedi… - Heliyon, 2023 - cell.com
Addiction is a worldwide problem that has a negative impact on society by imposing
significant costs on health care, public security, and the deactivation of the community …
significant costs on health care, public security, and the deactivation of the community …
Differences of physical vs. psychological stress: evidences from glucocorticoid receptor expression, hippocampal subfields injury, and behavioral abnormalities
Y Li, J Qin, J Yan, N Zhang, Y Xu, Y Zhu… - Brain imaging and …, 2019 - Springer
The glucocorticoid receptor (GR) is the main effector of the activation of the hypothalamus-
pituitary-adrenal (HPA) axis, which is caused by different types of stress that can be divided …
pituitary-adrenal (HPA) axis, which is caused by different types of stress that can be divided …
Repeated oxytocin treatment during abstinence inhibited context-or restraint stress-induced reinstatement of methamphetamine-conditioned place preference and …
J Cai, X Che, T Xu, Y Luo, M Yin, X Lu, C Wu… - Experimental …, 2022 - Elsevier
Propensity to relapse, even after long-term abstinence, is a crucial feature of
methamphetamine (METH) abuse. We and other laboratories have reported that acute …
methamphetamine (METH) abuse. We and other laboratories have reported that acute …
Spectral power and theta-gamma coupling in the basolateral amygdala related with methamphetamine conditioned place preference in mice
The basolateral amygdala (BLA) plays a crucial role in conditioned place preference (CPP)
for addictive drugs. However, neural signaling associated with methamphetamine (METH) …
for addictive drugs. However, neural signaling associated with methamphetamine (METH) …
The neural, behavioral, and epidemiological underpinnings of comorbid alcohol use disorder and post-traumatic stress disorder
HN Carlson, JL Weiner - International review of neurobiology, 2021 - Elsevier
Alcohol use disorder (AUD) and (PTSD) frequently co-occur and individuals suffering from
this dual diagnosis often exhibit increased symptom severity and poorer treatment outcomes …
this dual diagnosis often exhibit increased symptom severity and poorer treatment outcomes …
Smaller left hippocampal subfield CA1 volume is associated with reported childhood physical and/or sexual abuse in major depression: a pilot study
M Yuan, H Rubin-Falcone, X Lin, MM Rizk… - Journal of affective …, 2020 - Elsevier
Background Smaller hippocampal volumes are reported in adults with major depressive
disorder (MDD) and in reported childhood abuse. The hippocampus is a complex structure …
disorder (MDD) and in reported childhood abuse. The hippocampus is a complex structure …
The antagonism of corticotropin-releasing factor receptor-1 in brain suppress stress-induced propofol self-administration in rats
Z Dong, G Zhang, S Xiang, C Jiang, Z Chen… - Frontiers in Behavioral …, 2021 - frontiersin.org
Propofol addiction has been detected in humans and rats, which may be facilitated by stress.
Corticotropin-releasing factor acts through the corticotropin-releasing factor (CRF) receptor …
Corticotropin-releasing factor acts through the corticotropin-releasing factor (CRF) receptor …
Effect of acute and chronic restraint stress on electrical activity of prefrontal cortex neurons in the reinstatement of extinguished methamphetamine-induced …
Increased vulnerability to drug abuse has been observed after exposure to stress and the
prefrontal cortex (PFC) plays a major role in the control of the stress response and reward …
prefrontal cortex (PFC) plays a major role in the control of the stress response and reward …
Concomitant abuse of methadone and methamphetamine could impair spatial learning and memory in male rats
Methadone maintenance therapy (MMT) has been considered as an effective medication for
opioid dependence. However there are reports of methamphetamine abuse among MMT …
opioid dependence. However there are reports of methamphetamine abuse among MMT …