Signal transduction cascades regulating fungal development and virulence

KB Lengeler, RC Davidson, C D'souza… - Microbiology and …, 2000 - Am Soc Microbiol
Cellular differentiation, mating, and filamentous growth are regulated in many fungi by
environmental and nutritional signals. For example, in response to nitrogen limitation …

MAP kinases in fungal pathogens

JR Xu - Fungal Genetics and Biology, 2000 - Elsevier
MAP kinases in eukaryotic cells are well known for transducing a variety of extracellular
signals to regulate cell growth and differentiation. Recently, MAP kinases homologous to the …

The MAP kinase signal transduction network in Candida albicans

RA Monge, E Roman, C Nombela, J Pla - Microbiology, 2006 - microbiologyresearch.org
MAP (mitogen-activated protein) kinase-mediated pathways are key elements in sensing
and transmitting the response of cells to environmental conditions by the sequential action of …

The BMP1 Gene Is Essential for Pathogenicity in the Gray Mold Fungus Botrytis cinerea

L Zheng, M Campbell, J Murphy… - Molecular Plant …, 2000 - Am Phytopath Society
In Magnaporthe grisea, a well-conserved mitogen-activated protein (MAP) kinase gene,
PMK1, is essential for fungal pathogenesis. In this study, we tested whether the same MAP …

Virulence genes in the pathogenic yeast Candida albicans

F Navarro-García, M Sánchez… - FEMS microbiology …, 2001 - academic.oup.com
In recent years, the incidence of fungal infections has been rising all over the world.
Although the amount of research in the field of pathogenic fungi has also increased, there is …

MAP kinase pathways as regulators of fungal virulence

E Román, DM Arana, C Nombela, R Alonso-Monge… - Trends in …, 2007 - cell.com
MAP kinases are dual phosphorylated protein kinases, present in eukaryotes, which
mediate differentiation programs and immune responses in mammalian cells. In pathogenic …

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

MD Leach, S Budge, L Walker, C Munro… - PLoS …, 2012 - journals.plos.org
Thermal adaptation is essential in all organisms. In yeasts, the heat shock response is
commanded by the heat shock transcription factor Hsf1. Here we have integrated unbiased …

Fungal sex and pathogenesis

G Butler - Clinical Microbiology Reviews, 2010 - Am Soc Microbiol
Human fungal pathogens are associated with diseases ranging from dandruff and skin
colonization to invasive bloodstream infections. The major human pathogens belong to the …

Msb2 Signaling Mucin Controls Activation of Cek1 Mitogen-Activated Protein Kinase in Candida albicans

E Román, F Cottier, JF Ernst, J Pla - Eukaryotic cell, 2009 - Am Soc Microbiol
We have characterized the role that the Msb2 protein plays in the fungal pathogen Candida
albicans by the use of mutants defective in the putative upstream components of the HOG …

The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans

F Navarro-García, B Eisman, SM Fiuza… - …, 2005 - microbiologyresearch.org
Candida albicans is an opportunistic pathogen that has adapted to live and grow in the
human body as its natural environment. Under these conditions, this fungus faces numerous …