Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …

SUMMARY β-Lactamases continue to be the leading cause of resistance to β-lactam
antibiotics among gram-negative bacteria. In recent years there has been an increased …

Extended-spectrum β-lactamases (ESBLs) are a group of plasmid-mediated, diverse,
complex and rapidly evolving enzymes that are posing a major therapeutic challenge today …

The β-lactamases are the major bacterial defense of gram-negative bacteria against β-
lactam antibiotics. This review details the many types of β-lactamases, explains how they …

Antimicrobial stewardship programs in hospitals seek to optimize antimicrobial prescribing
in order to improve individual patient care as well as reduce hospital costs and slow the …

The prevalence of antibiotic resistance among extended-spectrum β-lactamase (ESBL)-
producing Escherichia coli and Klebsiella pneumoniae has increased markedly in recent …

Background: Commonly encountered nosocomially acquired gram-negative bacteria,
especially Klebsiella pneumoniae, produce extended-spectrum β-lactamases (ESBLs) as an …

Recent years have witnessed a rapidly growing crisis in antimicrobial resistance, especially
among microorganisms that cause nosocomial infection. To better understand common risk …

Bloodstream infections (BSI) caused by extended-spectrum β-lactamase (ESBL)-producing
organisms markedly increase the rates of treatment failure and death. We conducted a …

Extended spectrum β-lactamases (ESBLs) are plasmid mediated, TEM and SHV derived
enzymes, first isolated in Western Europe in mid 1980s, most commonly in Klebsiella spp …