[HTML][HTML] Phage therapy: From biological mechanisms to future directions

SA Strathdee, GF Hatfull, VK Mutalik, RT Schooley - Cell, 2023 - cell.com
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Engineered living materials for advanced diseases therapy

X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

High-throughput fabrication of antimicrobial phage microgels and example applications in food decontamination

L Tian, K Jackson, L He, S Khan… - Nature …, 2024 - nature.com
Engineered by nature, biological entities are exceptional building blocks for biomaterials.
These entities can impart enhanced functionalities on the final material that are otherwise …

Modulating of bouligand structure and chirality constructed bionically based on the self-assembly of chitin whiskers

Y Luo, Y Li, K Liu, L Li, W Wen, S Ding… - …, 2023 - ACS Publications
Chitin can self-assemble into a liquid crystal phase with supramolecular chirality and
Bouligand structure, which is widely found in the exoskeletons of arthropods. However …

Gelatin-methacryloyl hydrogels containing turnip mosaic virus for fabrication of nanostructured materials for tissue engineering

I González-Gamboa, E Velázquez-Lam… - … in Bioengineering and …, 2022 - frontiersin.org
Current tissue engineering techniques frequently rely on hydrogels to support cell growth, as
these materials strongly mimic the extracellular matrix. However, hydrogels often need ad …

Self-assembling nanofibrous bacteriophage microgels as sprayable antimicrobials targeting multidrug-resistant bacteria

L Tian, L He, K Jackson, A Saif, S Khan, Z Wan… - Nature …, 2022 - nature.com
Nanofilamentous bacteriophages (bacterial viruses) are biofunctional, self-propagating, and
monodisperse natural building blocks for virus-built materials. Minifying phage-built …

Phage display for the detection, analysis, disinfection, and prevention of Staphylococcus aureus

L Tian, K Jackson, M Chan, A Saif, L He… - Smart …, 2022 - Wiley Online Library
Abstract The World Health Organization has designated Staphylococcus aureus as a global
health concern. This designation stems from the emergence of multiple drug‐resistant …

Identification of a specific phage as growth factor alternative promoting the recruitment and differentiation of MSCs in bone tissue regeneration

X Wang, X Zhu, D Wang, X Li, J Wang… - ACS Biomaterials …, 2023 - ACS Publications
Inefficient use and loss of exogenously implanted mesenchymal stem cells (MSCs) are
major concerns in MSCs-based bone tissue engineering. It is a promising approach to …

Current Advances in Viral Nanoparticles for Biomedicine

X Sun, T Tian, Y Lian, Z Cui - ACS nano, 2024 - ACS Publications
Viral nanoparticles (VNPs) have emerged as crucial tools in the field of biomedicine.
Leveraging their biological and physicochemical properties, VNPs exhibit significant …