Cilnidipine: A New Generation Ca2+ Channel Blocker with Inhibitory Action on Sympathetic Neurotransmitter Release

A Takahara - Cardiovascular therapeutics, 2009 - Wiley Online Library
Cilnidipine is a unique Ca2+ channel blocker with an inhibitory action on the sympathetic N‐
type Ca2+ channels, which is used for patients with hypertension in Japan. Cilnidipine has …

Sympathomodulatory effects of antihypertensive drug treatment

G Grassi - American Journal of Hypertension, 2016 - academic.oup.com
BACKGROUND An activation of sympathetic neural influences to the heart and peripheral
circulation has been shown to represent a hallmark of the essential hypertensive state …

Impact of resting heart rate on outcomes in hypertensive patients with coronary artery disease: findings from the INternational VErapamil-SR/trandolapril STudy …

R Kolloch, UF Legler, A Champion… - European heart …, 2008 - academic.oup.com
Aim To determine the relationship between resting heart rate (RHR) and adverse outcomes
in coronary artery disease (CAD) patients treated for hypertension with different RHR …

[HTML][HTML] Autonomic dysfunction in mild cognitive impairment: evidence from power spectral analysis of heart rate variability in a cross-sectional case-control study

P Nicolini, MM Ciulla, G Malfatto, C Abbate, D Mari… - PloS one, 2014 - journals.plos.org
Background Mild cognitive impairment (MCI) is set to become a major health problem with
the exponential ageing of the world's population. The association between MCI and …

Regression analysis between heart rate variability and baroreflex‐related vagus nerve activity in rats

TBJ Kuo, CJ Lai, YUT HUANG… - Journal of …, 2005 - Wiley Online Library
Introduction: Many previous studies have suggested that the high‐frequency (HF) power of
the heart rate variability may represent cardiac vagal activity although direct evidence of a …

[HTML][HTML] Ожирение и артериальная гипертония

ЕИ Асташкин, МГ Глезер - Проблемы женского здоровья, 2008 - medi.ru
РЕЗЮМЕ В обзоре анализируются роль ожирения в развитии артериальной
гипертонии и сердечно-сосудистых заболеваний, патофизиологические механизмы …

Effect of the renin–angiotensin system or calcium channel blockade on the circadian variation of heart rate variability, blood pressure and circulating catecholamines …

M Karas, Y Lacourcière, AR LeBlanc… - Journal of …, 2005 - journals.lww.com
Objective To determine the effects of 8 weeks of therapy with amlodipine, ramipril or
telmisartan on the autonomic system over 24 h in hypertensives. Methods After a placebo …

Elevated heart rate in cardiovascular diseases: a target for treatment?

P Palatini - Progress in cardiovascular diseases, 2009 - Elsevier
Heart rate is a major determinant of myocardial oxygen consumption and of cardiac work,
and thus reduction of heart rate may represent an important strategy for the treatment of …

High-sensitivity C-reactive protein is associated with insulin resistance and cardiovascular autonomic dysfunction in type 2 diabetic patients

F Anan, N Takahashi, M Nakagawa, T Ooie, T Saikawa… - Metabolism, 2005 - Elsevier
We tested the hypothesis that elevated levels of plasma high-sensitivity C-reactive protein
(HSCRP) are associated with insulin resistance/hyperinsulinemia and cardiovascular …

Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis

E Yamamoto, ZF Lai, T Yamashita, T Tanaka… - Journal of …, 2006 - journals.lww.com
Objective To examine the mechanism and significance of tachycardia-induced cardiac
damage, using azelnidipine, a relatively new dihydropyridine calcium channel blocker which …