Very recently, we postulated that the incorporation of citral into nanostructured lipid carrier
(NLC-Citral) improves solubility and delivery of the citral without toxic effects in vivo. Thus …

Loss of wild-type p53 function is widely accepted to be permissive for the development of
multinucleated giant cells. However, whether therapy-induced multinucleation is associated …

Nanotechnology-based drug delivery platforms have emerged as one of the promising
approaches for the diagnosis and treatment of cancers. Furthermore, significant …

Cancer nano-therapy has been progressing rapidly with the introduction of many novel drug
delivery systems. The previous study has reported on the in vitro cytotoxicity of citral-loaded …

A variety of novel indole-derived γ-hydroxy propiolate esters were designed, synthesized,
and evaluated for their anti-inflammatory activity in-vitro and in-vivo. According to the nitric …

Oxidative stress is an important mechanism in acute lung injury (ALI) induced by paraquat
(PQ), one of the most widely used herbicides in developing countries. In clinical prophylaxis …

Objective Radiotherapy is the traditional therapy for glioma patients. Glioma has poor
response to ionizing radiation (IR). Studying radiation-induced cell death can help in …

Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is a refractory
respiratory disease mainly attributed to multiple pathological factors such as oxidative stress …

Background: Glioma is the most common primary brain tumor with poor prognosis.
Temozolomide (TMZ) has been used with irradiation (IR) to treat gliomas. The aim of the …

Although the clonogenic assay is the traditional method in determination of the response of
cell lines to irradiation and in drawing the survival curves, but this method has some …