Cancer immunotherapy is a validated and critically important approach for treating patients
with cancer. Given the vast research and clinical investigation efforts dedicated to advancing …

Cancer immunotherapy has significantly flourished and revolutionized the limited
conventional tumor therapies, on account of its good safety and long-term memory ability …

Background Resistance to an immune checkpoint inhibitor (ICI) is a major obstacle in cancer
immunotherapy. The causes of ICI resistance include major histocompatibility complex …

Immune 'checkpoint'inhibitors can increase the activity of tumor-resident cytotoxic
lymphocytes and have revolutionized cancer treatment. Current therapies block inhibitory …

Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Background The function of major histocompatibility complex (MHC) molecules is to bind
peptide fragments derived from genomic mutations or pathogens and display them on the …

The immunotherapeutic treatment of various cancers with an increasing number of immune
checkpoint inhibitors (ICIs) has profoundly improved the clinical management of advanced …

Cancer immunotherapies have made much headway during the past decades. Techniques
including the immune checkpoint inhibition (ICI) and adoptive cell therapy (ACT) have …

Vaccination is an innovative strategy for cancer treatment by leveraging various components
of the patients' immunity to boost an anti-tumor immune response. Rationally designed …

Marching into the second decade after the approval of ipilimumab, it is clear that immune
checkpoint inhibitors (ICIs) have dramatically improved the prognosis of melanoma …