Mechanisms of deep brain stimulation

TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

[HTML][HTML] Deep brain stimulation programming for movement disorders: current concepts and evidence-based strategies

T Koeglsperger, C Palleis, F Hell, JH Mehrkens… - Frontiers in …, 2019 - frontiersin.org
Deep brain stimulation (DBS) has become the treatment of choice for advanced stages of
Parkinson's disease, medically intractable essential tremor, and complicated segmental and …

The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease

G Tinkhauser, A Pogosyan, S Little, M Beudel, DM Herz… - Brain, 2017 - academic.oup.com
Adaptive deep brain stimulation uses feedback about the state of neural circuits to control
stimulation rather than delivering fixed stimulation all the time, as currently performed. In …

New insights into the relationship between dopamine, beta oscillations and motor function

N Jenkinson, P Brown - Trends in neurosciences, 2011 - cell.com
Synchronised neuronal oscillations at beta frequencies are prevalent in the human motor
system, but their function is unclear. In this Opinion article, we propose that the levels of beta …

Pathological synchronization in Parkinson's disease: networks, models and treatments

C Hammond, H Bergman, P Brown - Trends in neurosciences, 2007 - cell.com
Parkinson's disease is a common and disabling disorder of movement owing to
dopaminergic denervation of the striatum. However, it is still unclear how this denervation …

Deep brain stimulation

JS Perlmutter, JW Mink - Annu. Rev. Neurosci., 2006 - annualreviews.org
Deep brain stimulation (DBS) has provided remarkable benefits for people with a variety of
neurologic conditions. Stimulation of the ventral intermediate nucleus of the thalamus can …

Deep brain stimulation for Parkinson's disease

AL Benabid - Current opinion in neurobiology, 2003 - Elsevier
Deep brain stimulation at high frequency was first used in 1997 to replace thalamotomy in
treating the characteristic tremor of Parkinson's disease, and has subsequently been applied …

Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients

A Eusebio, W Thevathasan, LD Gaynor… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a
highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of …

Uncovering the mechanism (s) of action of deep brain stimulation: activation, inhibition, or both

CC McIntyre, M Savasta, L Kerkerian-Le Goff… - Clinical …, 2004 - Elsevier
High-frequency deep brain stimulation (DBS) of the thalamus or basal ganglia represents an
effective clinical technique for the treatment of several medically refractory movement …

Programming deep brain stimulation for Parkinson's disease: the Toronto Western Hospital algorithms

M Picillo, AM Lozano, N Kou, RP Munhoz, A Fasano - Brain stimulation, 2016 - Elsevier
Background Deep brain stimulation (DBS) is an established and effective treatment for
Parkinson's disease (PD). After surgery, a number of extensive programming sessions are …