ROS generation in microglia: understanding oxidative stress and inflammation in neurodegenerative disease
DSA Simpson, PL Oliver - Antioxidants, 2020 - mdpi.com
Neurodegenerative disorders, such as Alzheimer's disease, are a global public health
burden with poorly understood aetiology. Neuroinflammation and oxidative stress (OS) are …
burden with poorly understood aetiology. Neuroinflammation and oxidative stress (OS) are …
Lutein and zeaxanthin and their roles in age-related macular degeneration—neurodegenerative disease
M Mrowicka, J Mrowicki, E Kucharska, I Majsterek - Nutrients, 2022 - mdpi.com
Lutein and zeaxanthin belong to the xanthophyll family of carotenoids, which are pigments
produced by plants. Structurally, they are very similar, differing only slightly in the …
produced by plants. Structurally, they are very similar, differing only slightly in the …
Antioxidant-rich natural fruit and vegetable products and human health
AIO Jideani, H Silungwe, T Takalani… - … Journal of Food …, 2021 - Taylor & Francis
Antioxidants are important ingredients that are present in fruits and vegetables (FAV). With
increased consumption of FAV in its raw and processed form, a predominantly plant-based …
increased consumption of FAV in its raw and processed form, a predominantly plant-based …
NF-κB in oxidative stress
K Lingappan - Current opinion in toxicology, 2018 - Elsevier
The transcription factor nuclear factor-κB (NF-κB) modulates gene expression in diverse
cellular processes such as innate immune response, embryogenesis and organ …
cellular processes such as innate immune response, embryogenesis and organ …
ROS and ROS‐mediated cellular signaling
J Zhang, X Wang, V Vikash, Q Ye, D Wu… - Oxidative medicine …, 2016 - Wiley Online Library
It has long been recognized that an increase of reactive oxygen species (ROS) can modify
the cell‐signaling proteins and have functional consequences, which successively mediate …
the cell‐signaling proteins and have functional consequences, which successively mediate …
Oxidative stress, consequences and ROS mediated cellular signaling in rheumatoid arthritis
There are numerous extra-and intra-cellular processes involved in the production of reactive
oxygen species (ROS). Augmented ROS generation can cause the damage of biomolecules …
oxygen species (ROS). Augmented ROS generation can cause the damage of biomolecules …
[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …
Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways
Activation of microglia cells in the brain contributes to neurodegenerative processes
promoted by many neurotoxic factors such as pro-inflammatory cytokines and nitric oxide …
promoted by many neurotoxic factors such as pro-inflammatory cytokines and nitric oxide …
Role of endogenous lipopolysaccharides in neurological disorders
Lipopolysaccharide (LPS) is a cell-wall immunostimulatory endotoxin component of Gram-
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …
Functional properties of spinach (Spinacia oleracea L.) phytochemicals and bioactives
JL Roberts, R Moreau - Food & function, 2016 - pubs.rsc.org
Overwhelming evidence indicates that diets rich in fruits and vegetables are protective
against common chronic diseases, such as cancer, obesity and cardiovascular disease …
against common chronic diseases, such as cancer, obesity and cardiovascular disease …