Morphological alterations of mitochondria may be related to metabolic and energy
deficiency in neurons in Alzheimer's disease and other neurodegenerative disorders …

Two views currently dominate research into cell function and regulation. Model I assumes
that cell behavior is quite similar to that expected for a watery bag of enzymes and ligands …

Two human Fzo-homologs, mitofusins Mfn1 and Mfn2, are shown by RT-PCR and western
blot to be ubiquitous mitochondrial proteins. Protease digestion experiments reveal that …

Formation of a novel structure, the aggresome, has been proposed to represent a general
cellular response to the presence of misfolded proteins (Johnston, JA, CL Ward, and RR …

Many cellular components are transported using a combination of the actin-and microtubule-
based transport systems. However, how these two systems work together to allow well …

Neurons transport and position mitochondria using a combination of saltatory, bidirectional
movements and stationary docking. Axonal mitochondria move along microtubules (MTs) …

Mitochondria are localized to regions of the cell where ATP consumption is high and are
dispersed according to changes in local energy needs. In addition to motion directed by …

In neuroendocrine PC-12 cells, evanescent-field fluorescence microscopy was used to track
motions of green fluorescent protein (GFP)-labeled actin or GFP-labeled secretory granules …

Morphological alterations of mitochondria may be related to metabolic and energy
deficiency in neurons in Alzheimer's disease (AD) and other neurodegenerative disorders …

Tunneling nanotube (TNT)-like structures are intercellular membranous bridges that mediate
the transfer of various cellular components including endocytic organelles. To gain further …