This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …

Radiobiological modelling has been a key part of radiation biology and therapy for many
decades, and many aspects of clinical practice are guided by tools such as the linear …

Background and purpose Recent observations in animal models show that ultra-high dose
rate (“FLASH”) radiation treatment significantly reduces normal tissue toxicity maintaining an …

FLASH radiotherapy is considered a new potential breakthrough in cancer treatment. Ultra‐
high dose rates (> 40 Gy/s) have been shown to reduce toxicity in the normal tissue without …

Since a few breakthroughs in the fundamental understanding of the effects of swift heavy
ions (SHIs) decelerating in the electronic stopping regime in the matter have been achieved …

Purpose The simulation of individual particle tracks and the chemical stage following water
radiolysis in biological tissue is an effective means of improving our knowledge of the …

Our understanding of radiation-induced cellular damage has greatly improved over the past
few decades. Despite this progress, there are still many obstacles to fully understand how …

The radiosensitivity of biological systems is strongly affected by the system oxygenation. On
the nanoscopic scale and molecular level, this effect is considered to be strongly related to …

The chemical stage of the Monte Carlo track-structure simulation code Geant4-DNA has
been revised and validated. The root-mean-square (RMS) empirical parameter that dictates …

Proton‐based radiotherapy is a modern technique for the treatment of solid tumors with
significantly reduced side effects to adjacent tissues. Biocompatible nanoparticles (NPs) with …