In the present review, we will discuss the recent advances in the understanding of the role of
histamine and histamine receptors in cancer biology. The controversial role of the …

High levels of histamine and histamine receptors (HRs), including H1R~ H4R, are found in
many different types of tumor cells and cells in the tumor microenvironment, suggesting their …

Light stimulus responsive therapies are based on a variety of low-toxic therapeutic agents
and produce anti-tumor effects only under external light stimulation, thus greatly reducing …

The conjugation of photosensitizer with a molecule specific to receptors over-expressed on
cancer cells is a promising approach for improving tumor selectivity in photodynamic therapy …

We have explored the intracellular cell organelle's structural alterations after photodynamic
treatment with chlorin p6‐histamine conjugate (Cp6‐his) in human oral cancer cells. Herein …

Animal models are valuable tools for studying human cancer as well as for preclinical trials.
The hamster model of chemically induced sequential oral carcinogenesis was developed by …

Cancer is ranked as the deadliest prime health issue, albeit with mammoth efforts to
panacea the ailment. To subdue the vast constraints in tumor therapy, one requires a …

Introduction Colorectal cancer is a highly aggressive and metastatic cancer with inadequate
clinical outcomes. Given the crucial role of histamine and histamine receptors in colorectal …

Background Oral cavity squamous cell carcinoma is a common cancer of the head and neck
region. Due to the frequency of diagnoses, high rate of mortality, mutilating nature of classic …

Oral squamous cell carcinoma (OSCC), the most common oral malignancy, shows an
increasing rate of incidence worldwide. In spite of the recent advances in cancer research …