Motivation The interactions among various types of cells play critical roles in cell functions
and the maintenance of the entire organism. While cell–cell interactions are traditionally …

Translating the exponentially growing amount of omics data into knowledge usable for a
personalized medicine approach poses a formidable challenge. In this article—taking …

The semantic web depends on the use of ontologies to let electronic systems interpret
contextual information. Optimally, the handling and access of ontologies should be …

Predicting phenotypes using genome-wide genetic variation and gene expression data is
useful in several fields, such as human biology and medicine, as well as in crop and …

Identifying molecular targets of a drug is an essential process for drug discovery and
development. The recent in-silico approaches are usually based on the structure information …

Background In multicellular organisms, an intercellular signaling network communicates
information from the environment or distant tissues to defined target cells. Intercellular …

Bioinformatics tools are today an indispensable part of life-science research. There is a
huge demand of intuitively usable bioinformatics tools, which enable experimental …

Protein functional annotation consists in associating proteins with textual descriptors
elucidating their biological roles. The bulk of annotation is done via automated procedures …

Zusammenfassung Durch Experimente und deren Beobachtungen entstehen
experimentelle Daten. Durch Massenexperimente–wie zum Beispiel Gensequenzierungen …