Hydrogel scaffolds for tissue engineering: Progress and challenges

IM El-Sherbiny, MH Yacoub - Global Cardiology Science and Practice, 2013 - qscience.com
Designing of biologically active scaffolds with optimal characteristics is one of the key factors
for successful tissue engineering. Recently, hydrogels have received a considerable interest …

Hydrogels in regenerative medicine

BV Slaughter, SS Khurshid, OZ Fisher… - Advanced …, 2009 - Wiley Online Library
Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …

[HTML][HTML] Making neurons, made easy: The use of Neurogenin-2 in neuronal differentiation

AJ Hulme, S Maksour, MSC Glover, S Miellet, M Dottori - Stem Cell Reports, 2022 - cell.com
Directed neuronal differentiation of human pluripotent stem cells (hPSCs), neural
progenitors, or fibroblasts using transcription factors has allowed for the rapid and highly …

Microengineered hydrogels for tissue engineering

A Khademhosseini, R Langer - Biomaterials, 2007 - Elsevier
Hydrogels have been extensively used in various biomedical applications such as drug
delivery and biosensing. More recently the ability to engineer the size and shape of …

Methods for inducing embryoid body formation: in vitro differentiation system of embryonic stem cells

H Kurosawa - Journal of bioscience and bioengineering, 2007 - Elsevier
When cultured in suspension without antidifferentiation factors, embryonic stem (ES) cells
spontaneously differentiate and form three-dimensional multicellular aggregates called …

Interfacing silicon nanowires with mammalian cells

W Kim, JK Ng, ME Kunitake, BR Conklin… - Journal of the American …, 2007 - ACS Publications
We present the first demonstration of a direct interface of silicon nanowires with mammalian
cells such as mouse embryonic stem (mES) cells and human embryonic kidney (HEK 293T) …

Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates

MD Ungrin, C Joshi, A Nica, C Bauwens, PW Zandstra - PloS one, 2008 - journals.plos.org
Background Human embryonic stem cells (hESC) should enable novel insights into early
human development and provide a renewable source of cells for regenerative medicine …

A cell-laden microfluidic hydrogel

Y Ling, J Rubin, Y Deng, C Huang, U Demirci, JM Karp… - Lab on a Chip, 2007 - pubs.rsc.org
The encapsulation of mammalian cells within the bulk material of microfluidic channels may
be beneficial for applications ranging from tissue engineering to cell-based diagnostic …

Micromolding of shape-controlled, harvestable cell-laden hydrogels

J Yeh, Y Ling, JM Karp, J Gantz, A Chandawarkar… - Biomaterials, 2006 - Elsevier
Encapsulation of mammalian cells within hydrogels has great utility for a variety of
applications ranging from tissue engineering to cell-based assays. In this work, we present a …

Controlled differentiation of stem cells

NS Hwang, S Varghese, J Elisseeff - Advanced drug delivery reviews, 2008 - Elsevier
The extracellular microenvironment plays a significant role in controlling cellular behavior.
Identification of appropriate biomaterials that support cellular attachment, proliferation and …