Rapid nerve conduction requires the coating of axons by a tightly packed multilayered
myelin membrane. In the central nervous system, myelin is formed from cellular processes …

Dendritic cells (DCs) are considered the most potent antigen-presenting cells. DCs control
the activation of T cells (TCs) in the lymph nodes. This process involves forming a …

The decreased efficiency of immune responses in older people is partly a consequence of
alterations in T lymphocyte functions caused by modifications in the early events of signal …

Adoptive cell therapy (ACT) achieves substantial efficacy in the treatment of hematological
malignancies and solid tumours, while enormous endeavors have been made to reduce …

Rheumatoid Arthritis (RA) is a chronic autoimmune inflammatory disease that affects largely
synovial joints. It has been postulated that activated autoreactive CD4 T cells play a key role …

The pathogenesis of Streptococcus suis infection, a major swine and human pathogen, is
only partially understood and knowledge on the host adaptive immune response is critically …

The immunological synapse (IS) is a superstructure formed during T cell activation at the
zone of contact between T cells and dendritic cells (DCs). The IS includes specific molecular …

I. ABSTRACT Transcriptome-wide association studies (TWAS) have proven to be a powerful
tool to identify genes associated with human diseases by aggregating cis-regulatory effects …

B cells are essential to the adaptive immune system for providing the humoral immunity
against cohorts of pathogens. The presentation of antigen to the B cell receptor (BCR) leads …

RNA interference (RNAi) is a post-transcriptional pathway in which double-stranded RNA
(dsRNA) triggers the degradation of complementary mRNA in the cytoplasm of eukaryotic …