The “missing heritability”—Problem in psychiatry: Is the interaction of genetics, epigenetics and transposable elements a potential solution?
D van Calker, T Serchov - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Psychiatric disorders exhibit an enormous burden on the health care systems worldwide
accounting for around one-third of years lost due to disability among adults. Their etiology is …
accounting for around one-third of years lost due to disability among adults. Their etiology is …
Can Epigenetics Predict Drug Efficiency in Mental Disorders?
G Ben David, Y Amir, R Salalha, L Sharvit… - Cells, 2023 - mdpi.com
Psychiatric disorders affect millions of individuals and their families worldwide, and the costs
to society are substantial and are expected to rise due to a lack of effective treatments …
to society are substantial and are expected to rise due to a lack of effective treatments …
Ceremonial ayahuasca in amazonian retreats—mental health and epigenetic outcomes from a six-month naturalistic study
SGD Ruffell, N Netzband, WF Tsang, M Davies… - Frontiers in …, 2021 - frontiersin.org
Ayahuasca is a natural psychoactive brew, used in traditional ceremonies in the Amazon
basin. Recent research has indicated that ayahuasca is pharmacologically safe and its use …
basin. Recent research has indicated that ayahuasca is pharmacologically safe and its use …
[HTML][HTML] Accelerated aging in the brain, epigenetic aging in blood, and polygenic risk for schizophrenia
Schizophrenia patients show signs of accelerated aging in cognitive and physiological
domains. Both schizophrenia and accelerated aging, as measured by MRI brain images and …
domains. Both schizophrenia and accelerated aging, as measured by MRI brain images and …
Conserved DNA Methylation Signatures in Early Maternal Separation and in Twins Discordant for CO2 Sensitivity
F Giannese, A Luchetti, G Barbiera, V Lampis… - Scientific reports, 2018 - nature.com
Respiratory and emotional responses to blood-acidifying inhalation of CO2 are markers of
some human anxiety disorders, and can be enhanced by repeatedly cross-fostering (RCF) …
some human anxiety disorders, and can be enhanced by repeatedly cross-fostering (RCF) …
Rethinking the epigenetic framework to unravel the molecular pathology of schizophrenia
A Cariaga-Martinez, R Alelú-Paz - International Journal of Molecular …, 2017 - mdpi.com
Schizophrenia is a complex mental disorder whose causes are still far from being known.
Although researchers have focused on genetic or environmental contributions to the …
Although researchers have focused on genetic or environmental contributions to the …
[HTML][HTML] A characteristic cerebellar biosignature for bipolar disorder, identified with fully automatic machine learning
GV Thomaidis, K Papadimitriou, S Michos… - IBRO Neuroscience …, 2023 - Elsevier
Background Transcriptomic profile differences between patients with bipolar disorder and
healthy controls can be identified using machine learning and can provide information about …
healthy controls can be identified using machine learning and can provide information about …
Epigenetic and schizophrenia
A Cariaga-Martinez, R Alelú-Paz - Psychotic disorders-An …, 2018 - books.google.com
Schizophrenia is a complex psychiatric disorder characterised by the presence of positive,
negative and cognitive symptoms that lack a unifying neuropathology. The absence of …
negative and cognitive symptoms that lack a unifying neuropathology. The absence of …
Identifying Bipolar patients from controls, using post-mortem cerebellum gene expression data and fully Automated Machine Learning
GV Thomaidis, S Michos, K Papadimitriou… - medRxiv, 2022 - medrxiv.org
Objective Complex machine learning classification algorithms using transcriptome data from
post-mortem cerebellar tissue of bipolar patients and unaffected controls, have been …
post-mortem cerebellar tissue of bipolar patients and unaffected controls, have been …
[PDF][PDF] Rethinking schizophrenia through the lens of evolution: shedding light on the enigma
A Cariaga-Martinez, K Gutiérrez… - Research Ideas and …, 2018 - riojournal.com
Schizophrenia refers to a complex psychiatric illness characterized by the heterogenic
presence of positive, negative and cognitive symptoms occurring in all human societies. The …
presence of positive, negative and cognitive symptoms occurring in all human societies. The …