Background Obesity affects the course of critical illnesses. We aimed to estimate the
association of obesity with the severity and mortality in coronavirus disease 2019 (COVID …

Metabolic abnormalities such as dyslipidemia, hyperinsulinemia, or insulin resistance and
obesity play key roles in the induction and progression of type 2 diabetes mellitus (T2DM) …

The efficacy of the vaccines varies between individuals and populations. The
immunogenicity of the vaccine is influenced by various factors, including host factors …

Cellular senescence is a cell fate that occurs in response to numerous types of stress and
can promote tissue repair or drive inflammation and disruption of tissue homeostasis …

Abstract Coronavirus disease 2019 (Covid-19) has affected millions of people and may
disproportionately affect those with hypertension and diabetes. Because of inadequate …

Background Obesity is associated with enhanced inflammation. However, investigation in
human subcutaneous white adipose tissue (scWAT) is limited and the mechanisms by which …

The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

Background: The coronavirus disease 2019 (COVID-19) pandemic has recently led to
worldwide research efforts to identify subjects at greater risk of developing more severe …

Adaptation of the innate immune system has been recently acknowledged, explaining
sustained changes of innate immune responses. Such adaptation is termed trained …

Exosomes are nano-sized vesicles secreted by most cells that contain a variety of biological
molecules, such as lipids, proteins and nucleic acids. They have been recognized as …