Impact of air pollution on intestinal redox lipidome and microbiome

J Feng, S Cavallero, T Hsiai, R Li - Free Radical Biology and Medicine, 2020 - Elsevier
Air pollution is a rising public health issue worldwide. Cumulative epidemiological and
experimental studies have shown that exposure to air pollution such as particulate matter …

Neuroendocrine regulation of air pollution health effects: emerging insights

SJ Snow, AR Henriquez, DL Costa… - Toxicological …, 2018 - academic.oup.com
Air pollutant exposures are linked to cardiopulmonary diseases, diabetes, metabolic
syndrome, neurobehavioral conditions, and reproductive abnormalities. Significant effort is …

Multi-omics signatures of the human early life exposome

L Maitre, M Bustamante, C Hernández-Ferrer… - Nature …, 2022 - nature.com
Environmental exposures during early life play a critical role in life-course health, yet the
molecular phenotypes underlying environmental effects on health are poorly understood. In …

Estimating daily full-coverage near surface O3, CO, and NO2 concentrations at a high spatial resolution over China based on S5P-TROPOMI and GEOS-FP

Y Wang, Q Yuan, T Li, L Zhu, L Zhang - ISPRS Journal of Photogrammetry …, 2021 - Elsevier
Abstract The Near Surface Concentrations (NSC) of O 3, CO, and NO 2 are crucial
worldwide indicators of air quality. However, current frameworks devised for the estimation …

Ozone exposure increases circulating stress hormones and lipid metabolites in humans

DB Miller, AJ Ghio, ED Karoly, LN Bell… - American journal of …, 2016 - atsjournals.org
Rationale: Air pollution has been associated with increased prevalence of type 2 diabetes;
however, the mechanisms remain unknown. We have shown that acute ozone exposure in …

Subchronic exposure to concentrated ambient PM2. 5 perturbs gut and lung microbiota as well as metabolic profiles in mice

Z Ran, Y An, JI Zhou, J Yang, Y Zhang, J Yang… - Environmental …, 2021 - Elsevier
Exposure to ambient fine particular matter (PM2. 5) are linked to an increased risk of
metabolic disorders, leading to enhanced rate of many diseases, such as inflammatory …

Ambient PM2. 5 species and ultrafine particle exposure and their differential metabolomic signatures

FL Nassan, C Wang, RS Kelly, JA Lasky-Su… - Environment …, 2021 - Elsevier
Background The metabolomic signatures of short-and long-term exposure to PM 2.5 have
been reported and linked to inflammation and oxidative stress. However, little is known …

1H NMR-based metabolomics study on repeat dose toxicity of fine particulate matter in rats after intratracheal instillation

Y Zhang, H Hu, Y Shi, X Yang, L Cao, J Wu… - Science of the Total …, 2017 - Elsevier
Systemic metabolic effects and toxicity mechanisms of ambient fine particulate matter (PM
2.5) remain uncertain. In order to investigate the mechanisms in PM 2.5 toxicity, we explored …

Advances in understanding mechanisms underlying mitochondrial structure and function damage by ozone

T Wu, Z Li, Y Wei - Science of The Total Environment, 2023 - Elsevier
Mitochondria are double-membraned organelles found in eukaryotic cells. The integrity of
mitochondrial structure and function determines cell destiny. Mitochondria are also the …

Stress drivers of glucose dynamics during ozone exposure measured using radiotelemetry in rats

AR Henriquez, SJ Snow, TW Jackson… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Inhaled irritant air pollutants may trigger stress-related metabolic dysfunction
associated with altered circulating adrenal-derived hormones. Objectives: We used …