Molecular pathogenesis of intrahepatic cholestasis of pregnancy

J Xiao, Z Li, Y Song, Y Sun, H Shi… - Canadian Journal of …, 2021 - Wiley Online Library
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy‐specific liver disease. The
maternal symptoms are characterized by skin pruritus and elevated bile acids, causing …

[HTML][HTML] The pathological mechanisms of estrogen-induced cholestasis: current perspectives

Y Zu, J Yang, C Zhang, D Liu - Frontiers in Pharmacology, 2021 - frontiersin.org
Estrogens are steroid hormones with a wide range of biological activities. The excess of
estrogens can lead to decreased bile flow, toxic bile acid (BA) accumulation, subsequently …

[HTML][HTML] Prevalence and risk factors of intrahepatic cholestasis of pregnancy in a Chinese population

XX Gao, MY Ye, Y Liu, JY Li, L Li, W Chen, X Lu… - Scientific reports, 2020 - nature.com
Studies on the risk factors for intrahepatic cholestasis of pregnancy (ICP) in a population-
based cohort are lacking. We assess the prevalence and risk factors of ICP in a Chinese …

Prevalence, risk factors and adverse perinatal outcomes for Chinese women with intrahepatic cholestasis of pregnancy: a large cross-sectional retrospective study

K Wu, B Yin, S Li, X Zhu, B Zhu - Annals of Medicine, 2022 - Taylor & Francis
Background Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-
related liver disorder and may cause adverse perinatal outcomes. This large cross-sectional …

[HTML][HTML] Bile acids in intrahepatic cholestasis of pregnancy

M Majsterek, M Wierzchowska-Opoka, I Makosz… - Diagnostics, 2022 - mdpi.com
Intrahepatic cholestasis of pregnancy (ICP) is the most common, reversible, and closely
related to pregnancy condition characterized by elevated levels of bile acids (BAs) in blood …

[HTML][HTML] Guidelines for the management of cholestatic liver diseases (2021)

L Lu, Chinese Medical Association - Journal of Clinical and …, 2022 - ncbi.nlm.nih.gov
Abstract In 2015, the Chinese Society of Hepatology and the Chinese Society of
Gastroenterology issued a consensus statement on the diagnosis and management of …

Maternal hepatitis B infection status and adverse pregnancy outcomes: a retrospective cohort analysis

K Wu, H Wang, S Li, H Zhang, B Zhu - Archives of Gynecology and …, 2020 - Springer
Purpose To investigate the association between maternal HBsAg-positive status and
pregnancy outcomes. Methods The study enrolled women with singleton pregnancies who …

Society for Maternal-Fetal Medicine consult series# 56: hepatitis C in pregnancy—updated guidelines: replaces consult number 43, November 2017

SK Dotters-Katz, JA Kuller, BL Hughes… - American Journal of …, 2021 - Elsevier
In the United States, it is estimated that 1% to 4% of pregnant women are infected with
hepatitis C virus, which carries approximately a 5% risk of transmission from mother to infant …

[HTML][HTML] Sex-dependent differences in cholestasis: why estrogen signaling may be a key pathophysiological driver

AG Ismail, L Kennedy, H Francis - The American Journal of Pathology, 2023 - Elsevier
Primary Biliary Cholangitis (PBC) and Primary Sclerosing Cholangitis (PSC) are cholestatic
liver diseases with significant clinical impact with debilitating symptomology and mortality …

[HTML][HTML] A Chinese longitudinal maternity cohort study (2013–2021) on intrahepatic cholestasis phenotypes: Risk associations from environmental exposure to …

HZ Sun, H Tang, J Fang, H Dai, H Zhao, S Xu… - Journal of Hazardous …, 2024 - Elsevier
Intrahepatic cholestasis of pregnancy (ICP) is an idiopathic disease that occurs during mid-
to-late pregnancy and is associated with various adverse pregnancy outcomes, including …