Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Understanding and assessing endocrine response to stress is crucial to human performance
analysis, stress-related disorder diagnosis, and mental health monitoring. Current …

A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of
the newly evolved prefrontal cortex (PFC). Exposure to acute, uncontrollable stress …

Theoretical conceptualizations of awe suggest this emotion can be more positive or negative
depending on specific appraisal processes. However, the emergent scientific study of awe …

Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …