Sortase enzymes in Gram‐positive bacteria

T Spirig, EM Weiner, RT Clubb - Molecular microbiology, 2011 - Wiley Online Library
In Gram‐positive bacteria proteins are displayed on the cell surface using sortase enzymes.
These cysteine transpeptidases join proteins bearing an appropriate sorting signal to …

The double life of group B Streptococcus: asymptomatic colonizer and potent pathogen

B Armistead, E Oler, KA Waldorf, L Rajagopal - Journal of molecular biology, 2019 - Elsevier
Group B streptococcus (GBS) is a β-hemolytic gram-positive bacterium that colonizes the
lower genital tract of approximately 18% of women globally as an asymptomatic member of …

Understanding the regulation of Group B Streptococcal virulence factors

L Rajagopal - Future microbiology, 2009 - Taylor & Francis
Bacterial infections remain a significant threat to the health of newborns and adults. Group B
Streptococci (GBS) are Gram-positive bacteria that are common asymptomatic colonizers of …

Dual Role for Pilus in Adherence to Epithelial Cells and Biofilm Formation in Streptococcus agalactiae

Y Konto-Ghiorghi, E Mairey, A Mallet, G Duménil… - PLoS …, 2009 - journals.plos.org
Streptococcus agalactiae is a common human commensal and a major life-threatening
pathogen in neonates. Adherence to host epithelial cells is the first critical step of the …

Mucosal Adhesion Properties of the Probiotic Lactobacillus rhamnosus GG SpaCBA and SpaFED Pilin Subunits

I von Ossowski, J Reunanen, R Satokari… - Applied and …, 2010 - Am Soc Microbiol
Lactobacillus rhamnosus GG is a well-established Gram-positive probiotic strain, whose
health-benefiting properties are dependent in part on prolonged residence in the …

A tale of two pili: assembly and function of pili in bacteria

KA Kline, KW Dodson, MG Caparon, SJ Hultgren - Trends in microbiology, 2010 - cell.com
Bacterial pili have long been recognized as mediators of initial host–pathogen interactions
important for the progression of Gram-negative bacterial diseases. An appreciation of the …

Bacterial Pili exploit integrin machinery to promote immune activation and efficient blood-brain barrier penetration

A Banerjee, BJ Kim, EM Carmona, AS Cutting… - Nature …, 2011 - nature.com
Abstract Group B Streptococcus (GBS) is the leading cause of meningitis in newborn infants.
Bacterial cell surface appendages, known as pili, have been recently described in …

[HTML][HTML] Pili of gram-positive bacteria: roles in host colonization

C Danne, S Dramsi - Research in microbiology, 2012 - Elsevier
In the last decade, pili, which are encoded within pathogenicity islands, have been found in
many Gram-positive bacteria, including the major streptococcal and enterococcal …

Group B streptococcus: virulence factors and pathogenic mechanism

Y Liu, J Liu - Microorganisms, 2022 - mdpi.com
Group B Streptococcus (GBS) or Streptococcus agalactiae is a major cause of neonatal
mortality. When colonizing the lower genital tract of pregnant women, GBS may cause …

Specific Involvement of Pilus Type 2a in Biofilm Formation in Group B Streptococcus

CD Rinaudo, R Rosini, CL Galeotti, F Berti, F Necchi… - PloS one, 2010 - journals.plos.org
Streptococcus agalactiae is the primary colonizer of the anogenital mucosa of up to 30% of
healthy women and can infect newborns during delivery and cause severe sepsis and …