Cardiovascular disease is the major cause of morbidity and mortality in Westernised
societies. It is well known that the aetiology of this devastating disorder involves both genetic …

Objectives The aim of the study was to evaluate the correlation between left ventricular
hypertrophy and the gene polymorphism of angiotensin-converting enzyme (ACE) intron …

Background: Chronic alcohol abuse has a dose-dependent toxic effect on the myocardium,
leading to alcoholic cardiomyopathy. The fact that only a minority of persons with chronic …

Cardiac hypertrophy and remodeling in relation to ACE and angiotensinogen genes
genotypes in Chinese dialysis patients. Background Genetic polymorphisms of the …

Hypertensive cardiac remodeling is illustrated by increased left ventricular (LV) mass index
values and/or relative wall thickness (RWT) values> 0.42, and functionally by isolated …

Aims Cardiac angiotensin-I converting enzyme (ACE) activity is influenced by the ACE I/D
polymorphism. Evidence suggests that the DD-genotype may be a risk factor for cardiac …

Cardiac hypertrophy is an adaptive process which occurs as a result of increased stress
endured by the heart and this cardiac remodeling serves as a reactive mechanism to …

Objectives In this prospective population-based study, we tested the possible interaction
between chronic kidney disease (CKD) and left atrium volume index (LAVI) in predicting …

Aims To investigate the additive prognostic impact of both forearm endothelial dysfunction
and left ventricular mass (LVM) for future cardiovascular events. Methods and results We …

The renin angiotensin system was demonstrated to play a significant role in the genesis of
hypertension and regulation of vascular tone over 100 years ago. The early investigations …