[HTML][HTML] Mechanism and clinical application of thymosin in the treatment of lung cancer

Y Liu, J Lu - Frontiers in Immunology, 2023 - frontiersin.org
Cancer is one of the leading causes of death worldwide. The burden of cancer on public
health is becoming more widely acknowledged. Lung cancer has one of the highest …

[HTML][HTML] Cancer chemoprevention through Frizzled receptors and EMT

K Sompel, A Elango, AJ Smith, MA Tennis - Discover Oncology, 2021 - Springer
Frizzled (FZD) transmembrane receptors are well known for their role in β-catenin signaling
and development and now understanding of their role in the context of cancer is growing …

Smoking status during first‐line immunotherapy and chemotherapy in NSCLC patients: A case–control matched analysis from a large multicenter study

A Cortellini, A De Giglio, K Cannita… - Thoracic …, 2021 - Wiley Online Library
Background Improved outcome in tobacco smoking patients with non‐small cell lung cancer
(NSCLC) following immunotherapy has previously been reported. However, little is known …

[HTML][HTML] The β-blocker carvedilol prevents benzo (a) pyrene-induced lung toxicity, inflammation and carcinogenesis

A Shahid, M Chen, C Lin, BT Andresen, C Parsa… - Cancers, 2023 - mdpi.com
Simple Summary Benzo (a) pyrene is a ubiquitously present environmental contaminant that
induces lung cancer after being converted into active metabolites via aryl hydrocarbon …

PPARgamma agonism inhibits progression of premalignant lesions in a murine lung squamous cell carcinoma model

LD Dwyer‐Nield, DG McArthur… - … Journal of Cancer, 2022 - Wiley Online Library
The N‐nitroso‐trischloroethylurea (NTCU)‐induced mouse model of squamous lung
carcinoma recapitulates human disease from premalignant dysplasia through invasive …

First-in-human study of inhaled Azacitidine in patients with advanced non-small cell lung cancer

H Cheng, Y Zou, CD Shah, N Fan, TD Bhagat… - Lung Cancer, 2021 - Elsevier
Abstract Background Aerosolized Azacitidine has been shown to inhibit orthotopic lung
cancer growth and induce re-expression of methylated tumor suppressor genes in murine …

Association between clinicopathological parameters and S100A8/A9 expression according to smoking history in patients with non-small cell lung cancer

SB Cho, IK Kim, CD Yeo, SH Lee - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Lung cancer is a major cause of cancer-related deaths worldwide, and
chronic inflammation caused by cigarette smoke plays a crucial role in the development and …

[HTML][HTML] Synergistic effect of cannabidiol with dasatinib on lung cancer by SRC/PI3K/AKT signal pathway

Q Ye, C Gui, D Jin, J Zhang, J Zhang, N Ma… - Biomedicine & …, 2024 - Elsevier
Dasatinib-related resistance frequently occurs and may lead to the failure of chemotherapy;
thus, dose interruptions are necessary. Cannabidiol (CBD) has potential for integration with …

The Circ_CARM1 controls cell migration by regulating CTNNBIP1 in anti-benzo [a] pyrene-trans-7, 8-dihydrodiol-9, 10-epoxide-transformed 16HBE cells

Z Xiao, Z Yang, M Xu, W Li, X Chen, K Chen, M Li, X Lu… - Toxicology Letters, 2021 - Elsevier
Abstract Background Circular RNAs (circRNAs) have an important role in the development
and progression of human tumors, including lung cancer. Yet, their role in lung cancer …

[HTML][HTML] Liriopesides B induces apoptosis and cell cycle arrest in human non‑small cell lung cancer cells

H Sheng, W Lv, L Zhu, L Wang… - International …, 2020 - spandidos-publications.com
Although significant progress has been made in the treatment of lung cancer, it remains the
leading cause of cancer‑associated mortality. Liriopesides B (LPB) is a natural product …