We propose a neural connectomics strategy called Fluorescent In-Situ Sequencing of
Barcoded Individual Neuronal Connections (FISSEQ-BOINC), leveraging fluorescent in situ …

We analyze the scaling and cost-performance characteristics of current and projected
connectomics approaches, with reference to the potential implications of recent advances in …

In recent years, multiple serial histology techniques were developed to enable whole rodent
brain imaging in 3-D. The main driving forces behind the emergence of these imaging …

Rapid advances in high-resolution, high-throughput 3D microscopy techniques in the past
decade have opened up new avenues for brain research. One such technique developed in …

Introduction Studies of categorical decision-making attempt to understand behavior by
probing how different features of complex and changing environments guide the selection of …

Analyzing mammalian brain image can help to understand the interaction between cerebral
blood flow and its surrounding tissue. However, extracting the geometry of the vasculature …

We present a novel, parallelizable algorithm capable of automatically reconstructing and
calculating anatomical statistics of cerebral vascular networks embedded in large volumes …

Accurate estimation of neuronal count and distribution is central to the understanding of the
organization and layout of cortical maps in the brain, and changes in the cell population …

The 3D reconstruction of neurovascular network plays an important role in understanding
the functions of the blood vessels in different brain regions. Many techniques have been …

Cardiovascular disease is a widespread systemic disease that contributes substantially to
morbidity and mortality rates both in the United States and across the globe, with …