Androgens during infancy, childhood, and adolescence: physiology and use in clinical practice

KA Mason, MJ Schoelwer, AD Rogol - Endocrine Reviews, 2020 - academic.oup.com
We provide an in-depth review of the role of androgens in male maturation and
development, from the fetal stage through adolescence into emerging adulthood, and …

Hormone therapy in hypospadias surgery: a systematic review

JMB Netto, CEPF Ferrarez, AAS Leal, S Tucci Jr… - Journal of Pediatric …, 2013 - Elsevier
Surgical correction of hypospadias is proposed to improve the aesthetic and functional
quality of the penis. Hormone therapy preceding surgical correction is indicated to obtain …

[PDF][PDF] The effect of parenteral testosterone administration prior to hypospadias surgery: a prospective, randomized and controlled study

SA Asgari, MR Safarinejad, F Poorreza, AS Asl… - J Pediatr Urol, 2015 - academia.edu
The goal of hypospadias surgery is to provide a functionally and cosmetically normal penis.
Whether this goal will be to the patient's satisfaction depends largely on the original …

Congenital micropenis: etiology and management

MR Stancampiano, K Suzuki, S O'Toole… - Journal of the …, 2022 - academic.oup.com
In the newborn, penile length is determined by a number of androgen dependent and
independent factors. The current literature suggests that there are interracial differences in …

Intrauterine growth restriction and hypospadias: is there a connection?

MJ Chen, CG Macias, SK Gunn, JE Dietrich… - International journal of …, 2014 - Springer
Hypospadias is one of the most common congenital malformations of the genitourinary tract
in males. It is an incomplete fusion of urethral folds early in fetal development and may be …

Quantifying glans width changes in response to preoperative androgen stimulation in patients undergoing hypospadias repair

S Mittal, S Eftekharzadeh, SS Christianson… - The Journal of …, 2022 - auajournals.org
Purpose: Testosterone (T) administration prior to hypospadias surgery to increase glans size
remains controversial. Understanding T's effect on glans width (GW) is essential to …

Biometry of the hypospadic penis after hormone therapy (testosterone and estrogen): a randomized, double-blind controlled trial

KC de Castro Paiva, AN Bastos, LP Miana… - Journal of Pediatric …, 2016 - Elsevier
Introduction The use of preoperative hormonal stimulation before hypospadias surgery aims
to increase penile size and achieve better surgical results; however, the rules are not clear …

Advancing precision in penile length measurement: evidence-based synthesis of stretched penile length INdicator technique (SPLINT)

P Goel, P Choudhury, KK Saroya, V Jain… - Journal of Indian …, 2024 - journals.lww.com
Purpose: The purpose of this study was to synthesize evidence and propose a technique for
estimation of stretched penile length (SPL) applicable to children. Materials and Methods …

Therapeutic strategies for patients with micropenis or penile dysmorphic disorder

O Kayes, M Shabbir, D Ralph, S Minhas - Nature Reviews Urology, 2012 - nature.com
Micropenis in adults is defined as a stretched length of< 7.5 cm. Many aetiologies exist,
including congenital and endocrinological causes as well as pathological conditions, such …

The influence of perioperative factors on primary severe hypospadias repair

M Castagnetti, A El-Ghoneimi - Nature Reviews Urology, 2011 - nature.com
Hypospadias is one of the most common congenital malformations of the male genitalia.
Severe cases present with associated curvature greater than 30° and the meatus opening …