Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease

K Matsushita, SH Ballew, AYM Wang… - Nature Reviews …, 2022 - nature.com
Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …

Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

CM Shanahan, MH Crouthamel, A Kapustin… - Circulation …, 2011 - Am Heart Assoc
Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

[HTML][HTML] Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

T Isakova, P Wahl, GS Vargas, OM Gutiérrez… - Kidney international, 2011 - Elsevier
Fibroblast growth factor 23 (FGF23) regulates phosphorus metabolism and is a strong
predictor of mortality in dialysis patients. FGF23 is thought to be an early biomarker of …

Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease

T Isakova, H Xie, W Yang, D Xie, AH Anderson… - Jama, 2011 - jamanetwork.com
Context A high level of the phosphate-regulating hormone fibroblast growth factor 23 (FGF-
23) is associated with mortality in patients with end-stage renal disease, but little is known …

[HTML][HTML] Vascular calcification in chronic kidney disease: different bricks in the wall?

M Vervloet, M Cozzolino - Kidney international, 2017 - Elsevier
A high prevalence of vascular calcification (VC) and a high incidence of cardiovascular
events are two key complications of chronic kidney disease. Since most observational …

Klotho deficiency causes vascular calcification in chronic kidney disease

MC Hu, M Shi, J Zhang, H Quiñones… - Journal of the …, 2011 - journals.lww.com
Soft-tissue calcification is a prominent feature in both chronic kidney disease (CKD) and
experimental Klotho deficiency, but whether Klotho deficiency is responsible for the …

Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic …

SC Palmer, A Hayen, P Macaskill, F Pellegrini… - Jama, 2011 - jamanetwork.com
Context Clinical practice guidelines on the management of mineral and bone disorders due
to chronic kidney disease recommend specific treatment target levels for serum phosphorus …

Calcium metabolism in health and disease

M Peacock - Clinical Journal of the American society of …, 2010 - journals.lww.com
This brief review focuses on calcium balance and homeostasis and their relationship to
dietary calcium intake and calcium supplementation in healthy subjects and patients with …

A current understanding of vascular calcification in CKD

NJ Paloian, CM Giachelli - American Journal of Physiology …, 2014 - journals.physiology.org
Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have
significant cardiovascular morbidity and mortality that is in part due to the development of …