Outcomes of psychotic disorders are associated with high personal, familiar, societal and
clinical burden. There is thus an urgent clinical and societal need for improving those …

Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …

We report the current best estimate of the effects of cognitive behavior therapy (CBT) in the
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …

Importance Individuals can be classified as being at clinical high risk (CHR) for psychosis if
they meet at least one of the ultra–high-risk (UHR) inclusion criteria (brief limited intermittent …

The transdiagnostic expression of psychotic experiences in common mental disorder
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …

Importance The overall effect of At Risk Mental State (ARMS) services for the detection of
individuals who will develop psychosis in secondary mental health care is undetermined …

An accurate detection of individuals at clinical high risk (CHR) for psychosis is a prerequisite
for effective preventive interventions. Several psychometric interviews are available, but their …

Background: The individual risk of developing psychosis after being tested for clinical high-
risk (CHR) criteria (posttest risk of psychosis) depends on the underlying risk of the disease …

Abstract The Clinical High-Risk state for psychosis (CHR-P) paradigm was introduced about
2 decades ago. Over this period of time accumulating knowledge has been gained …