Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Deracemization, which converts a racemate into its single enantiomer without separation of
the intermediate, has gained renewed interest in asymmetric synthesis with its inherent …

As the enzyme toolbox for biocatalysis has expanded, so has the potential for the
construction of powerful enzymatic cascades for efficient and selective synthesis of target …

Amine transaminases constitute an important class of enzymes for the synthesis of chiral
amines, which are commonly used as building blocks in pharmaceutical compounds and …

Amine dehydrogenase-catalyzed reductive amination of prochiral ketones with ammonia is
a promising method for the synthesis of optically pure amines in the pharmaceutical and fine …

Chiral amines are crucial precursors of various pharmaceutical drugs, fine chemicals, and
bioactive molecules. Amine dehydrogenases (AmDHs) have attracted increasing attention …

The integration of oxidation and enantioselective reduction enables a redox deracemization
to directly access enantioenriched products from their corresponding racemates. However …

We developed a multienzyme biocatalytic cascade with high atom efficiency and a self-
sufficient redox network for the synthesis of nylon monomers without adding auxiliary …

Deracemisation methods have demonstrated their importance in the preparation of chiral
compounds in the last few years. In order to resolve a racemic mixture in a dynamic sense …

Abstract Pyridoxal-5′-phosphate-dependent transaminases of fold type IV (class IV) are
promising enzymes for (R)-selective amination of organic compounds. Transaminases of …